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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1103390	Ardea Biosciences Inc.	RDEA	Pharmaceutical Preparations (2834)	943200380

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1202094	Kimberly Manhard	4939 Directors Place San Diego CA 92121	Svp, Regulatory & Dev Ops	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2012-05-29	5,000	$3.90	14,970	No	4	M	Direct
Common Stock	Disposition	2012-05-29	5,000	$31.89	9,970	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	M	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Employee Stock Option (Right to Buy)	Disposition	2012-05-29	5,000	$0.00	5,000	$3.90

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
5,000		2016-12-20	No	4	M	Direct

Footnotes

The stock option exercise and sale of common stock reported in this Form 4 was effected pursuant to a Rule 10b5-1 plan dated as of June 22, 2011.
Includes 239 shares acquired under the Ardea Biosciences, Inc. 2000 Employee Stock Purchase Plan on May 14, 2012.
The range of sales prices received was $31.875 to $31.91. Upon request by the SEC staff, the issuer, or any security holder of the issuer, full information will be provided regarding the number of shares purchased or sold at each separate price.
25% of the shares subject to the stock option vested and became exercisable on December 21, 2007. The remaining shares vest in equal monthly installments over the following 3 years.