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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1401667	Puma Biotechnology Inc.	PBYI	Pharmaceutical Preparations (2834)	770683487

Insiders

Cik	Name	Reported Address	Director	Officer	Large Shareholder	Other
1163846	Adage Capital Partners, L.p.	200 Clarendon Street, 52Nd Floor Boston MA 02116	No	No	Yes	No
1165408	Adage Capital Partners Gp Llc	200 Clarendon Street 52Nd Floor Boston MA 02116	No	No	Yes	No
1403403	Adage Capital Advisors, L.l.c.	200 Clarendon Street 52Nd Floor Boston MA 02116	No	No	Yes	No
1403404	Robert Atchinson	200 Clarendon Street 52Nd Floor Boston MA 02116	No	No	Yes	No
1403413	Phillip Gross	200 Clarendon Street 52Nd Floor Boston MA 02116	No	No	Yes	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock, Par Value $0.0001 Per Share ("Common Stock")	Acquisiton	2012-04-25	200,000	$13.97	3,500,000	No	4	P	Indirect	See Footnote

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	P	Indirect	See Footnote

Footnotes

Adage Capital Partners GP, L.L.C., a Delaware limited liability company ("ACPGP"), serves as the general partner of Adage Capital Partners, L.P., a Delaware limited partnership (the "Fund"), and as such has discretion over the portfolio securities beneficially owned by the Fund. Adage Capital Advisors, L.L.C., a Delaware limited liability company ("ACA"), is the managing member of ACPGP and directs ACPGP's operations. Robert Atchinson and Phillip Gross are the managing members of ACPGP and ACA and general partners of the Fund. ACPGP, ACA, Robert Atchinson and Phillip Gross disclaim beneficial ownership of the reported securities except to the extent of their pecuniary interest therein.