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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
882796	Biocryst Pharmaceuticals Inc	BCRX	Biological Products, (No Disgnostic Substances) (2836)	621413174

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1395238	David Mccullough	4505 Emperor Blvd. Suite 200 Durham NC 27703	Vp	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2012-01-03	60,624	$1.20	66,624	No	4	M	Direct
Common Stock	Disposition	2012-01-03	60,624	$2.45	6,000	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	M	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Emp. Stock Option (Right to Buy)	Disposition	2012-01-03	60,624	$0.00	60,624	$1.20

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
9,376	2010-03-02	2019-03-02	No	4	M	Direct

Footnotes

The price in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $2.38 to $2.52. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares purchased at each price within the range for all transactions reported in this Form 4 utilizing an average weighted price.
Transacted under a 10b5-1 plan that was adopted on 12/16/2011.