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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1649904	Rhythm Pharmaceuticals Inc.	RYTM	Pharmaceutical Preparations (2834)	462159271

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1801372	Kayden Jennifer Lee	222 Berkeley Street, 12Th Floor Boston MA 02116	Evp, Head Of North America	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2023-08-07	8,591	$6.80	14,517	No	4	M	Direct
Common Stock	Disposition	2023-08-07	11,223	$24.18	3,294	No	4	S	Direct
Common Stock	Acquisiton	2023-08-09	1,718	$6.80	5,012	No	4	M	Direct
Common Stock	Disposition	2023-08-09	1,718	$24.66	3,294	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	S	Direct
No	4	M	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (Right to Buy)	Disposition	2023-08-07	8,591	$0.00	8,591	$6.80
Common Stock	Stock Option (Right to Buy)	Disposition	2023-08-09	1,718	$0.00	1,718	$6.80

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
73,909		2032-02-08	No	4	M	Direct
72,191		2032-02-08	No	4	M	Direct

Footnotes

Includes 986 shares acquired under Issuer's Employee Stock Purchase Plan on February 28, 2023.
The sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 8, 2023.
The stock options were granted on February 9, 2022. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.