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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1856587	Kristen Ambrose	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Svp & Chief Accounting Officer	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Disposition	2023-02-24	502	$289.12	8,510	No	4	F	Direct
Common Stock	Disposition	2023-02-27	982	$287.25	7,528	No	4	S	Direct
Common Stock	Disposition	2023-02-27	183	$288.68	7,345	No	4	S	Direct
Common Stock	Disposition	2023-02-27	42	$289.63	7,303	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	F	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Footnotes

Transaction made pursuant to Ms. Ambrose's company approved trading plan under Rule 10b5-1.
Ms. Ambrose undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $287.25 (range $286.79 to $287.71).
Open market sales reported on this line occurred at a weighted average price of $288.68 (range $288.24 to $289.17).