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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1557290	A Stuart Arbuckle	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Evp, Coo	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Disposition	2023-02-10	3,372	$294.33	92,880	No	4	F	Direct
Common Stock	Disposition	2023-02-13	5,990	$298.26	86,890	No	4	F	Direct
Common Stock	Disposition	2023-02-13	245	$296.44	86,645	No	4	S	Direct
Common Stock	Disposition	2023-02-13	2,028	$298.42	84,617	No	4	S	Direct
Common Stock	Disposition	2023-02-13	1,779	$299.26	82,838	No	4	S	Direct
Common Stock	Disposition	2023-02-13	835	$300.13	82,003	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	F	Direct
No	4	F	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Reported Non-Derivative Holdings

Sec. Name	Remaning Holdings	Nature of Ownership	Explanation
Common Stock	140	Indirect	401(k)

Footnotes

Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.
Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $296.44 (range $295.84 to $296.57).
Open market sales reported on this line occurred at a weighted average price of $298.42 (range $297.85 to $298.80).
Open market sales reported on this line occurred at a weighted average price of $299.26 (range $298.86 to $299.81).
Open market sales reported on this line occurred at a weighted average price of $300.13 (range $299.93 to $300.53).