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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1847529	Joy Liu	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Svp, General Counsel	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Disposition	2022-08-15	206	$300.26	13,146	No	4	S	Direct
Common Stock	Disposition	2022-08-15	698	$301.63	12,448	No	4	S	Direct
Common Stock	Disposition	2022-08-15	100	$302.35	12,348	No	4	S	Direct
Common Stock	Disposition	2022-08-15	700	$303.99	11,648	No	4	S	Direct
Common Stock	Disposition	2022-08-15	1,743	$305.01	9,905	No	4	S	Direct
Common Stock	Disposition	2022-08-15	300	$305.57	9,605	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Footnotes

Transaction made pursuant to Ms. Liu's company approved trading plan under Rule 10b5-1.
Ms. Liu undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $300.26 (range $300.00 to $300.28).
Open market sales reported on this line occurred at a weighted average price of $301.63 (range $301.23 to $302.01).
Open market sales reported on this line occurred at a weighted average price of $303.99 (range $303.48 to $304.46).
Open market sales reported on this line occurred at a weighted average price of $305.01 (range $304.54 to $305.53).
Open market sales reported on this line occurred at a weighted average price of $305.57 (range $305.55 to $305.58).