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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1847529	Joy Liu	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Svp, General Counsel	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Disposition	2022-05-16	25	$250.77	14,442	No	4	S	Direct
Common Stock	Disposition	2022-05-16	19	$251.57	14,423	No	4	S	Direct
Common Stock	Disposition	2022-05-16	20	$252.49	14,403	No	4	S	Direct
Common Stock	Disposition	2022-05-16	34	$253.87	14,369	No	4	S	Direct
Common Stock	Disposition	2022-05-16	35	$254.36	14,334	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Footnotes

Transaction made pursuant to Ms. Liu's company approved trading plan under Rule 10b5-1.
Ms. Liu undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $250.77 (range $250.00 to $250.90).
Open market sales reported on this line occurred at a weighted average price of $251.57 (range $251.05 to $251.81).
Open market sales reported on this line occurred at a weighted average price of $252.49 (range $252.12 to $253.11).
Open market sales reported on this line occurred at a weighted average price of $253.87 (range $253.14 to $254.13).
Open market sales reported on this line occurred at a weighted average price of $254.36 (range $254.15 to $254.57).