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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1847529	Joy Liu	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Svp, General Counsel	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Disposition	2022-04-29	17	$273.37	14,437	No	4	S	Direct
Common Stock	Disposition	2022-04-29	41	$274.75	14,396	No	4	S	Direct
Common Stock	Disposition	2022-04-29	30	$275.62	14,366	No	4	S	Direct
Common Stock	Disposition	2022-04-29	22	$276.72	14,344	No	4	S	Direct
Common Stock	Disposition	2022-04-29	10	$278.04	14,334	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Footnotes

Transaction made pursuant to Ms. Liu's company approved trading plan under Rule 10b5-1.
Ms. Liu undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $273.37 (range $273.13 to $273.87).
Open market sales reported on this line occurred at a weighted average price of $274.74 (range $274.20 to $275.14).
Open market sales reported on this line occurred at a weighted average price of $275.62 (range $275.22 to $276.19).
Open market sales reported on this line occurred at a weighted average price of $276.72 (range $276.31 to $277.06).