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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1334365	Yuchun Lee	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210		Yes	No	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2022-04-06	2,000	$81.54	3,875	No	4	M	Direct
Common Stock	Disposition	2022-04-06	17	$267.57	3,858	No	4	S	Direct
Common Stock	Disposition	2022-04-06	300	$270.67	3,558	No	4	S	Direct
Common Stock	Disposition	2022-04-06	1,600	$271.78	1,958	No	4	S	Direct
Common Stock	Disposition	2022-04-06	83	$272.84	1,875	No	4	S	Direct
Common Stock	Acquisiton	2022-04-07	2,000	$81.54	3,875	No	4	M	Direct
Common Stock	Disposition	2022-04-07	417	$272.76	3,458	No	4	S	Direct
Common Stock	Disposition	2022-04-07	500	$273.78	2,958	No	4	S	Direct
Common Stock	Disposition	2022-04-07	256	$275.26	2,702	No	4	S	Direct
Common Stock	Disposition	2022-04-07	727	$276.37	1,975	No	4	S	Direct
Common Stock	Disposition	2022-04-07	100	$277.02	1,875	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (Right to Buy)	Disposition	2022-04-06	2,000	$0.00	2,000	$81.54
Common Stock	Stock Option (Right to Buy)	Disposition	2022-04-07	2,000	$0.00	2,000	$81.54

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
14,000		2023-05-31	No	4	M	Direct
12,000		2023-05-31	No	4	M	Direct

Footnotes

Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.
Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $270.67 (range $270.42 to $270.88).
Open market sales reported on this line occurred at a weighted average price of $271.78 (range $271.43 to $272.33).
Open market sales reported on this line occurred at a weighted average price of $272.84 (range $272.56 to $272.97).
Fully vested.
Open market sales reported on this line occurred at a weighted average price of $272.76 (range $272.50 to $273.28).
Open market sales reported on this line occurred at a weighted average price of $273.78 (range $273.52 to $273.98).
Open market sales reported on this line occurred at a weighted average price of $275.26 (range $274.64 to $275.43).
Open market sales reported on this line occurred at a weighted average price of $276.37 (range $275.94 to $276.82).