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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1829069	Bastiano Sanna	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Evp, Cell & Genetic Therapies	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Disposition	2022-04-04	305	$267.10	46,763	No	4	S	Direct
Common Stock	Disposition	2022-04-04	257	$268.43	46,506	No	4	S	Direct
Common Stock	Disposition	2022-04-05	3,163	$275.23	43,343	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Footnotes

Transaction made pursuant to Mr. Sanna's company approved trading plan under Rule 10b5-1.
Mr. Sanna undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $267.10 (range $266.66 to $267.57).
Open market sales reported on this line occurred at a weighted average price of $268.43 (range $267.81 to $268.78).
Open market sales reported on this line occurred at a weighted average price of $275.23 (range $275.00 to $275.66).