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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1223348	Jr F Charles Wagner	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Evp & Chief Financial Officer	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Disposition	2022-04-01	300	$261.42	45,902	No	4	S	Direct
Common Stock	Disposition	2022-04-01	381	$263.67	45,521	No	4	S	Direct
Common Stock	Disposition	2022-04-01	1,142	$265.06	44,379	No	4	S	Direct
Common Stock	Disposition	2022-04-01	536	$265.95	43,843	No	4	S	Direct
Common Stock	Disposition	2022-04-01	223	$266.68	43,620	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Footnotes

Transaction made pursuant to Mr. Wagner's company approved trading plan under Rule 10b5-1.
Mr. Wagner undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $261.42 (range $261.04 to $261.80).
Open market sales reported on this line occurred at a weighted average price of $263.67 (range $263.45 to $264.42).
Open market sales reported on this line occurred at a weighted average price of $265.06 (range $264.53 to $265.48).
Open market sales reported on this line occurred at a weighted average price of $265.95 (range $265.55 to $266.47).
Open market sales reported on this line occurred at a weighted average price of $266.68 (range $266.55 to $266.83).