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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1649904	Rhythm Pharmaceuticals Inc.	RYTM	Pharmaceutical Preparations (2834)	462159271

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1774702	Yann Mazabraud	C/O Rhythm Pharmaceuticals, Inc. 222 Berkeley Street, 12Th Floor Boston MA 02116	Evp, Head Of International	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2022-02-11	2,032	$0.00	2,032	No	4	M	Direct
Common Stock	Disposition	2022-02-15	934	$6.10	1,098	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	M	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Restricted Stock Units	Disposition	2022-02-11	2,032	$0.00	2,032	$0.00

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
6,093			No	4	M	Direct

Footnotes

Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.
The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported Restricted Share Units.
The restricted stock units vest or have vested as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date.