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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1550395	David Altshuler	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Evp, Global Research And Cso	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Disposition	2022-02-10	3,518	$237.74	62,179	No	4	F	Direct
Common Stock	Disposition	2022-02-11	841	$233.92	61,338	No	4	S	Direct
Common Stock	Disposition	2022-02-11	757	$234.95	60,581	No	4	S	Direct
Common Stock	Disposition	2022-02-11	601	$236.28	59,980	No	4	S	Direct
Common Stock	Disposition	2022-02-11	98	$237.23	59,882	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	F	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Footnotes

Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.
Open market sales reported on this line occurred at a weighted average price of $233.92 (range $233.36 to $234.30).
Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $234.95 (range $234.47 to $235.28).
Open market sales reported on this line occurred at a weighted average price of $236.28 (range $235.84 to $236.74).