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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1223348	Jr F Charles Wagner	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Evp & Chief Financial Officer	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2022-02-01	3,698	$0.00	38,489	No	4	A	Direct
Common Stock	Acquisiton	2022-02-01	11,628	$0.00	50,117	No	4	A	Direct
Common Stock	Acquisiton	2022-02-01	10,262	$0.00	60,379	No	4	A	Direct
Common Stock	Disposition	2022-02-02	2,944	$250.07	57,435	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	A	Direct
No	4	A	Direct
No	4	A	Direct
No	4	S	Direct

Footnotes

Represents earned performance shares with respect to a performance stock unit award granted on 04/10/2019 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 02/01/2022 and the shares will vest on 02/24/2022.
Represents earned performance shares with respect to a performance stock unit award granted on 02/03/2021 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 02/01/2022 and the shares will vest in installments beginning on 02/17/2022.
Restricted stock unit award that vests in installments beginning on 02/24/2023.
Transaction made pursuant to Mr. Wagner's company approved trading plan under Rule 10b5-1.
Open market sales reported on this line occurred at a weighted average price of $250.07 (range $250.00 to $250.09).
Mr. Wagner undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.