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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1863127	Tyra Biosciences Inc.	TYRA	()	DE

Insiders

Cik	Name	Reported Address	Director	Officer	Large Shareholder	Other
1315082	Ra Capital Healthcare Fund Lp	C/O Ra Capital Management, L.p. 200 Berkeley Street, 18Th Floor Boston MA 02116	Yes	No	Yes	No
1346824	Ra Capital Management, L.p.	200 Berkeley Street 18Th Floor Boston MA 02116	Yes	No	Yes	No
1384859	Peter Kolchinsky	C/O Ra Capital Management, L.p. 200 Berkeley Street, 18Th Floor Boston MA 02116	Yes	No	Yes	No
1619841	M. Rajeev Shah	C/O Ra Capital Management, L.p. 200 Berkeley Street, 18Th Floor Boston MA 02116	Yes	No	Yes	No
1780117	Ra Capital Nexus Fund, L.p.	C/O Ra Capital Management, L.p. 200 Berkeley Street, 18Th Floor Boston MA 02116	Yes	No	Yes	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2021-09-17	4,047,120	$0.00	4,047,120	No	4	C	Indirect	See footnotes
Common Stock	Acquisiton	2021-09-17	1,250,000	$16.00	5,297,120	No	4	P	Indirect	See footnotes
Common Stock	Acquisiton	2021-09-17	1,496,613	$0.00	1,496,613	No	4	C	Indirect	See footnotes
Common Stock	Acquisiton	2021-09-17	442,721	$0.00	442,721	No	4	C	Indirect	See footnotes

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	C	Indirect	See footnotes
No	4	P	Indirect	See footnotes
No	4	C	Indirect	See footnotes
No	4	C	Indirect	See footnotes

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Series A Preferred Stock	Disposition	2021-09-17	1,011,370	$0.00	2,626,932	$0.00
Common Stock	Series A Preferred Stock	Disposition	2021-09-17	393,940	$0.00	1,023,219	$0.00
Common Stock	Series A Preferred Stock	Disposition	2021-09-17	170,448	$0.00	442,721	$0.00
Common Stock	Series B Preferred Stock	Disposition	2021-09-17	546,773	$0.00	1,420,188	$0.00
Common Stock	Series B Preferred Stock	Disposition	2021-09-17	182,257	$0.00	473,394	$0.00

Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
No	4	C	Indirect
No	4	C	Indirect
No	4	C	Indirect
No	4	C	Indirect
No	4	C	Indirect

Footnotes

On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.
These securities are held directly by RA Capital Healthcare Fund, L.P. (the "Fund").
These securities are held directly by RA Capital Nexus Fund, L.P. (the "Nexus Fund").
RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund, the Nexus Fund, and a separately managed account (the "Account"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky, and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein.
These securities are held directly by the Account.