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Filing Details

Accession Number:: 0001193805-11-000856
Form Type:: 4
Zero Holdings:: No
Publication Time:: 2011-05-06 21:59:32
Reporting Period:: 2011-05-04

Filing Date:: 2011-05-06
Accepted Time:: 2011-05-06 21:59:32
SEC Url:: Form 4 Filing

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
930553	Ista Pharmaceuticals Inc	ISTA	Pharmaceutical Preparations (2834)	330511719

Insiders

Cik	Name	Reported Address	Director	Officer	Large Shareholder	Other
1009258	Deerfield Management Co /Ny	780 Third Avenue, 37Th Floor New York NY 10017	No	No	Yes	Yes
1010823	Deerfield Capital Lp	780 Third Avenue 37Th Floor New York NY 10017	No	No	Yes	Yes
1061970	Ltd International Deerfield	C/O Citi Fund Services (Bvi) Ltd Bison Court, Po Box 3460, Road Town Tortola D8 --	No	No	Yes	Yes
1301041	Deerfield Partners, Lp	780 Third Avenue 37Th Floor New York NY 10017	No	No	Yes	Yes
1352546	E James Flynn	780 Third Avenue 37Th Floor New York NY 10017	No	No	Yes	Yes
1354395	Deerfield Special Situations Fund, L.p.	780 3Rd Avenue 37Th Floor New York NY 10017	No	No	Yes	Yes
1354397	Ltd International Fund Situations Special Deerfield	C/O Citi Hedge Fund Services (Bvi) Ltd Bison Court, P.o. Box 3460 Road Town, Tortola D8 -	No	No	Yes	Yes
1397526	P L Fund Design Private Deerfield	780 3Rd Ave 37Th Fl New York NY 10017	No	No	Yes	Yes
1407589	Deerfield Private Design International, L.p.	780 Third Avenue, 37Th Floor New York NY 10017	No	No	Yes	Yes

Reported Non-Derivative Transactions

Show Other Fields >>

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Disposition	2011-05-04	211,717	$10.52	144,295	No	4	S	Indirect	Through Deerfield Special Situations Fund, L.P.
Common Stock	Disposition	2011-05-04	328,995	$10.52	218,368	No	4	S	Indirect	Through Deerfield Special Situations Fund International Limited
Common Stock	Disposition	2011-05-04	297,290	$10.54	458,491	No	4	S	Indirect	Through Deerfield Private Design Fund, L.P.
Common Stock	Disposition	2011-05-04	478,946	$10.54	738,686	No	4	S	Indirect	Through Deerfield Private Design International, L.P.
Common Stock	Disposition	2011-05-05	10,265	$10.50	134,030	No	4	S	Indirect	Through Deerfield Special Situations Fund, L.P.
Common Stock	Disposition	2011-05-05	15,535	$10.50	202,833	No	4	S	Indirect	Through Deerfield Special Situations Fund International Limited
Common Stock	Disposition	2011-05-05	32,616	$10.50	425,875	No	4	S	Indirect	Through Deerfield Private Design Fund, L.P.
Common Stock	Disposition	2011-05-05	52,551	$10.50	686,135	No	4	S	Indirect	Through Deerfield Private Design International, L.P.
Common Stock	Disposition	2011-05-06	26,375	$10.60	107,655	No	4	S	Indirect	Through Deerfield Special Situations Fund, L.P.
Common Stock	Disposition	2011-05-06	39,916	$10.60	162,917	No	4	S	Indirect	Through Deerfield Special Situations Fund International Limited
Common Stock	Disposition	2011-05-06	83,814	$10.60	342,061	No	4	S	Indirect	Through Deerfield Private Design Fund, L.P.
Common Stock	Disposition	2011-05-06	135,036	$10.60	551,099	No	4	S	Indirect	Through Deerfield Private Design International, L.P.

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	S	Indirect	Through Deerfield Special Situations Fund, L.P.
No	4	S	Indirect	Through Deerfield Special Situations Fund International Limited
No	4	S	Indirect	Through Deerfield Private Design Fund, L.P.
No	4	S	Indirect	Through Deerfield Private Design International, L.P.
No	4	S	Indirect	Through Deerfield Special Situations Fund, L.P.
No	4	S	Indirect	Through Deerfield Special Situations Fund International Limited
No	4	S	Indirect	Through Deerfield Private Design Fund, L.P.
No	4	S	Indirect	Through Deerfield Private Design International, L.P.
No	4	S	Indirect	Through Deerfield Special Situations Fund, L.P.
No	4	S	Indirect	Through Deerfield Special Situations Fund International Limited
No	4	S	Indirect	Through Deerfield Private Design Fund, L.P.
No	4	S	Indirect	Through Deerfield Private Design International, L.P.

Reported Non-Derivative Holdings

Sec. Name	Remaning Holdings	Nature of Ownership	Explanation
Common Stock	80,000	Direct

Footnotes

This Form 4 is being filed by the undersigned as well as the entities listed on the Joint Filer Information Statement attached as an exhibit hereto (the "Reporting Persons").
Deerfield Capital, L.P. is the general partner of Deerfield Partners, L.P., Deerfield Special Situations Fund, L.P. and Deerfield Private Design Fund, L.P. and Deerfield Private Design International, L.P. (the "Domestic Funds"). James E. Flynn is the managing member of the general partner of Deerfield Capital, L.P. In accordance with Instruction 4(b)(iv) to Form 4, the entire amount of the Issuer's securities held by the Domestic Funds are reported herein. For purposes of Section 16 of the Securities Exchange Act of 1934, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its indirect pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise.
Deerfield Management Company, L.P. is the investment manager of Deerfield International Limited and Deerfield Special Situations Fund International Limited (the "Offshore Funds"). James E. Flynn is the managing member of the general partner of Deerfield Management Company, L.P. In accordance with Instruction 4(b)(iv) to Form 4, the entire amount of the Issuer's securities held by the Offshore Funds are reported herein. For purposes of Section 16 of the Securities Exchange Act of 1934, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its indirect pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise.
The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.24 to $10.84, inclusive. The reporting persons undertake to provide to ISTA Pharmaceuticals, Inc., any security holder of ISTA Pharmaceuticals, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the rages set forth in column 4 of this Form 4 and in the footnotes herein containing transaction price ranges.
The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.24 to 10.84, inclusive.
The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.55 to 10.65, inclusive.