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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1417926	Invo Bioscience Inc.	INVO	Surgical & Medical Instruments & Apparatus (3841)	204036208

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1535264	Awm Investment Company, Inc.	527 Madison Avenue Suite 2600 New York NY 10022		No	No	Yes	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2021-04-08	15,000	$4.08	1,067,820	No	4	P	Indirect	By Limited Partnerships
Common Stock	Acquisiton	2021-04-09	27,811	$4.08	1,095,631	No	4	P	Indirect	By Limited Partnerships
Common Stock	Acquisiton	2021-04-12	13,146	$4.00	1,108,777	No	4	P	Indirect	By Limited Partnerships
Common Stock	Acquisiton	2021-04-13	5,800	$3.97	1,114,577	No	4	P	Indirect	By Limited Partnerships
Common Stock	Acquisiton	2021-04-14	17,152	$3.95	1,131,729	No	4	P	Indirect	By Limited Partnerships
Common Stock	Acquisiton	2021-04-15	322	$3.85	1,132,051	No	4	P	Indirect	By Limited Partnerships
Common Stock	Acquisiton	2021-04-16	9,001	$3.83	1,141,052	No	4	P	Indirect	By Limited Partnership
Common Stock	Acquisiton	2021-04-19	5,801	$3.64	1,146,853	No	4	P	Indirect	By Limited Partnerships
Common Stock	Acquisiton	2021-04-20	3,500	$3.90	1,150,353	No	4	P	Indirect	By Limited Partnerships
Common Stock	Acquisiton	2021-04-27	3,800	$4.44	1,154,153	No	4	P	Indirect	By Limited Partnerships
Common Stock	Acquisiton	2021-05-04	465	$3.85	1,154,618	No	4	P	Indirect	By Limited Partnerships
Common Stock	Acquisiton	2021-05-04	2,457	$3.85	1,157,075	No	4	P	Indirect	By Limited Partnerships
Common Stock	Acquisiton	2021-05-06	1,000	$3.85	1,158,075	No	4	P	Indirect	By Limited Partnerships

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	P	Indirect	By Limited Partnerships
No	4	P	Indirect	By Limited Partnerships
No	4	P	Indirect	By Limited Partnerships
No	4	P	Indirect	By Limited Partnerships
No	4	P	Indirect	By Limited Partnerships
No	4	P	Indirect	By Limited Partnerships
No	4	P	Indirect	By Limited Partnership
No	4	P	Indirect	By Limited Partnerships
No	4	P	Indirect	By Limited Partnerships
No	4	P	Indirect	By Limited Partnerships
No	4	P	Indirect	By Limited Partnerships
No	4	P	Indirect	By Limited Partnerships
No	4	P	Indirect	By Limited Partnerships

Footnotes

This is a weighted average price.
AWM Investment Company, Inc., a Delaware Corporation (AWM), is the investment adviser to Special Situations Fund III QP, L.P. (QP), Special Situations Cayman Fund, L.P. (Cay) and Special Situations Life Sciences Fund, L.P. (LS). (LS and together with QP and Cay, the Funds). As the investment adviser to the Funds, AWM holds sole voting and investment power over 399,809 shares of Common Stock of the Issuer (the Shares) held by QP, 133,266 Shares held by Cay and 625,000 Shares held by LS.
Austin W. Marxe (Marxe), David M. Greenhouse (Greenhouse) and Adam C. Stettner (Stettner) are the controlling principals of AWM.The reporting person disclaims beneficial ownership of the Shares, except to the extent of its pecuniary interest therein. This report shall notbe deemed an admission that the reporting person is the beneficial owner of the securities reported herein for purposes of Section 16 of theSecurities Exchange Act of 1934, as amended, or for any other purpose.