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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1597264	Blueprint Medicines Corp	BPMC	Pharmaceutical Preparations (2834)	000000000

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1769740	Ariel Hurley	C/O Blueprint Medicines Corporation 45 Sidney Street Cambridge MA 02139	Principal Accounting Officer	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2021-03-01	3,187	$0.00	13,171	No	4	A	Direct
Common Stock	Acquisiton	2021-03-01	1,400	$1.87	14,571	No	4	M	Direct
Common Stock	Acquisiton	2021-03-01	300	$8.80	14,871	No	4	M	Direct
Common Stock	Disposition	2021-03-01	1,700	$99.51	13,171	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	A	Direct
No	4	M	Direct
No	4	M	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (Right to Buy)	Acquisiton	2021-03-01	6,375	$0.00	6,375	$100.13
Common Stock	Stock Option (Right to Buy)	Disposition	2021-03-01	1,400	$0.00	1,400	$1.87
Common Stock	Stock Option (Right to Buy)	Disposition	2021-03-01	300	$0.00	300	$8.80

Remaning Holdings	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
6,375	2031-03-01	No	4	A	Direct
5,754	2024-10-08	No	4	M	Direct
2,664	2025-02-10	No	4	M	Direct

Footnotes

The reported transaction involved the Reporting Person's receipt of a grant of 3,187 restricted stock units under Issuer's 2015 Stock Option and Incentive Plan.
Effected pursuant to a trading plan adopted on March 17, 2020 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.
The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $99.40 to $100.00 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
This option vests with respect to 1/48th of the shares underlying the option on April 1, 2021 and as to an additional 1/48th of the shares underlying the option each month thereafter.
This option was granted on October 8, 2014 and is fully vested as of the date hereof.
This option was granted on February 10, 2015 and is fully vested as of the date hereof.