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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1446372	M Paul Silva	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Svp & Chief Accounting Officer	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Disposition	2021-02-26	2,218	$212.42	12,666	No	4	F	Direct
Common Stock	Disposition	2021-03-01	1,026	$210.13	11,640	No	4	S	Direct
Common Stock	Disposition	2021-03-01	610	$211.45	11,030	No	4	S	Direct
Common Stock	Disposition	2021-03-01	915	$212.51	10,115	No	4	S	Direct
Common Stock	Disposition	2021-03-01	231	$213.12	9,884	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	F	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Reported Non-Derivative Holdings

Sec. Name	Remaning Holdings	Nature of Ownership	Explanation
Common Stock	169	Indirect	401(k)

Footnotes

Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.
Open market sales reported on this line occurred at a weighted average price of $210.13 (range $209.93 to $210.77).
Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $211.45 (range $210.96 to $211.95).
Open market sales reported on this line occurred at a weighted average price of $212.51 (range $211.96 to $212.85).
Open market sales reported on this line occurred at a weighted average price of $213.12 (range $212.96 to $213.27).