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Filing Details

Accession Number:: 0001567619-21-004320
Form Type:: 4
Zero Holdings:: No
Publication Time:: 2021-02-17 19:14:46
Reporting Period:: 2021-02-12

Accepted Time:: 2021-02-17 19:14:46
SEC Url:: Form 4 Filing

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1559053	Prothena Corp Public Ltd Co	PRTA	Pharmaceutical Preparations (2834)	000000000

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1587114	Ecor1 Capital, Llc	357 Tehama Street #3 San Francisco CA 94103		No	No	Yes	No

Reported Non-Derivative Transactions

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Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Ordinary Shares	Acquisiton	2021-02-12	62,500	$20.50	9,489,140	No	4	P	Indirect	See Note 1
Ordinary Shares	Acquisiton	2021-02-12	282,800	$20.08	9,771,940	No	4	P	Indirect	See Note 1
Ordinary Shares	Acquisiton	2021-02-16	89,200	$22.78	9,861,140	No	4	P	Indirect	See Note 1
Ordinary Shares	Acquisiton	2021-02-17	198,840	$23.46	10,059,980	No	4	P	Indirect	See Note 1

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	P	Indirect	See Note 1
No	4	P	Indirect	See Note 1
No	4	P	Indirect	See Note 1
No	4	P	Indirect	See Note 1

Reported Derivative Transactions

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Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Ordinary Shares	Call Option	Acquisiton	2021-02-17	2,500	$3.68	250,000	$30.00

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
2,500	2021-02-17	2021-06-30	No	4	P	Indirect

Footnotes

The filing persons (the "Filers") are EcoR1 Capital, LLC ("EcoR1"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. ("Qualified Fund"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (collectively, the "Funds"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 3 for itself, Mr. Nodelman and Qualified Fund. The Filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group, within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended. The Funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the Funds, and Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Filers disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein.
All of the Ordinary Shares purchased in this transaction were purchased by Qualified Fund. After this transaction, Qualified Fund owned 7,915,587 Ordinary Shares.
All of the Ordinary Shares purchased in this transaction were purchased by Qualified Fund. After this transaction, Qualified Fund owned 8,198,387 Ordinary Shares.
80,040 of the Ordinary Shares purchased in this transaction were purchased by Qualified Fund. After this transaction, Qualified Fund owned 8,278,427 Ordinary Shares.
166,926 of the Ordinary Shares purchased in this transaction were purchased by Qualified Fund. After this transaction, Qualified Fund owned 8,445,353 Ordinary Shares.
2,099 of the options purchased in this transaction were purchased by Qualified Fund. After this transaction, Qualified Fund owned 2,099 options to acquire 209,900 Ordinary Shares.