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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1274644	Tranzyme Inc	TZYM	Pharmaceutical Preparations (2834)	631192270

Insiders

Cik	Name	Reported Address	Director	Officer	Large Shareholder	Other
1170144	Quaker Bio Ventures Lp	2929 Arch Street Philadelphia PA 19104	No	No	Yes	No
1223034	Quaker Bioventures Capital Lp	2929 Arch Street Philadelphia PA 19104	No	No	Yes	No
1488182	D Brenda Gavin	2929 Arch Street Philadelphia PA 19104	Yes	No	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2011-04-06	2,189,791	$0.00	2,189,791	No	4	C	Direct
Common Stock	Acquisiton	2011-04-06	375,000	$4.00	2,564,791	No	4	P	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	C	Direct
No	4	P	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Series A Convertible Preferred Stock	Disposition	2011-04-06	15,328,551	$0.00	2,189,791	$0.00

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
0			No	4	C	Direct

Footnotes

Each share of the Issuer's Series A Convertible Preferred Stock automatically converted, for no additional consideration, into shares of Common Stock prior to the closing of the Issuer's initial public offering on a 7-for-1 basis, reflecting a 1-for-7 reverse stock split which became effective on March 31, 2011.
These securities are owned of recored by Quaker BioVentures, L.P. ("Quaker"). Quaker BioVentures Capital, L.P. is the managing partner of Quaker and has voting and dispositive power over the shares held by Quaker. Voting and investment decisions made by Quaker BioVentures Capital, L.P. with respect to the shares held by Quaker are made by an investment committee comprised of the following managers of Quaker BioVentures Capital, L.P.: Brenda D. Gavin, P. Sherrill Neff and Ira M. Lubert, each of whom disclaims beneficial ownership of such securities except to the extent of his or her pecuniary interest therein.
These shares were purchased in the Issuer's initial public offering.