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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1242825	M Jeffrey Leiden	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Executive Chairman	Yes	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2020-05-07	24,216	$187.53	70,872	No	4	M	Direct
Common Stock	Acquisiton	2020-05-07	35,499	$96.87	106,371	No	4	M	Direct
Common Stock	Acquisiton	2020-05-07	4,470	$91.05	110,841	No	4	M	Direct
Common Stock	Acquisiton	2020-05-07	24,349	$155.57	135,190	No	4	M	Direct
Common Stock	Disposition	2020-05-07	5,892	$267.52	129,298	No	4	S	Direct
Common Stock	Disposition	2020-05-07	24,617	$268.63	104,681	No	4	S	Direct
Common Stock	Disposition	2020-05-07	30,237	$269.52	74,444	No	4	S	Direct
Common Stock	Disposition	2020-05-07	13,885	$270.43	60,559	No	4	S	Direct
Common Stock	Disposition	2020-05-07	14,131	$271.61	46,428	No	4	S	Direct
Common Stock	Disposition	2020-05-07	5,607	$272.41	40,821	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	M	Direct
No	4	M	Direct
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (Right to Buy)	Disposition	2020-05-07	24,216	$0.00	24,216	$187.53
Common Stock	Stock Option (Right to Buy)	Disposition	2020-05-07	35,499	$0.00	35,499	$96.87
Common Stock	Stock Option (Right to Buy)	Disposition	2020-05-07	4,470	$0.00	4,470	$91.05
Common Stock	Stock Option (Right to Buy)	Disposition	2020-05-07	24,349	$0.00	24,349	$155.57

Remaning Holdings	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
24,215	2029-02-05	No	4	M	Direct
35,499	2024-07-14	No	4	M	Direct
98,336	2026-02-01	No	4	M	Direct
24,348	2028-02-05	No	4	M	Direct

Reported Non-Derivative Holdings

Sec. Name	Remaning Holdings	Nature of Ownership	Explanation
Common Stock	440	Indirect	401(k)

Footnotes

Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.
Open market sales reported on this line occurred at a weighted average price of $267.52 (range $266.97 to $267.94).
Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $268.83 (range $268.02 to $269.01).
Open market sales reported on this line occurred at a weighted average price of $269.52 (range $269.02 to $270.01).
Open market sales reported on this line occurred at a weighted average price of $270.43 (range $270.02 to $271.00).
Open market sales reported on this line occurred at a weighted average price of $271.61 (range $271.17 to $272.15).
Open market sales reported on this line occurred at a weighted average price of $272.41 (range $272.17 to $272.77).
Fully vested.