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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1242825	M Jeffrey Leiden	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Ceo & President	Yes	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Disposition	2019-02-04	1,300	$184.99	155,815	No	4	S	Direct
Common Stock	Disposition	2019-02-04	17,099	$186.10	138,716	No	4	S	Direct
Common Stock	Disposition	2019-02-04	12,951	$186.70	125,765	No	4	S	Direct
Common Stock	Disposition	2019-02-04	900	$187.91	124,865	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Reported Non-Derivative Holdings

Sec. Name	Remaning Holdings	Nature of Ownership	Explanation
Common Stock	440	Indirect	401(k)

Footnotes

Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.
Open market sales reported on this line occurred at a weighted average price of $184.99 (range $184.49 to $185.38).
Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $186.10 (range $185.55 to $186.38).
Open market sales reported on this line occurred at a weighted average price of $186.70 (range $186.39 to $187.29).
Open market sales reported on this line occurred at a weighted average price of $187.91 (range $187.51 to $188.25).