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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1674416	Crispr Therapeutics Ag	CRSP	Pharmaceutical Preparations (2834)	MA

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
875320	Vertex Pharmaceuticals Inc / Ma	50 Northern Avenue Boston MA 02210		No	No	Yes	No
1761216	Ltd (Europe) Pharmaceuticals Vertex	2 Kingdom St., 9Th Floor London X0 W2 6BD		No	No	Yes	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Shares	Acquisiton	2018-12-21	22,742	$22.58	5,272,742	No	4	P	Direct
Common Shares	Acquisiton	2018-12-24	2,603	$22.91	5,275,345	No	4	P	Direct
Common Shares	Acquisiton	2018-12-24	11,742	$23.18	5,287,087	No	4	P	Direct
Common Shares	Acquisiton	2018-12-24	53,655	$24.97	5,340,742	No	4	P	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	P	Direct
No	4	P	Direct
No	4	P	Direct
No	4	P	Direct

Footnotes

Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.
Represents the weighted average price. These shares were purchased in multiple transactions at prices ranging from $22.46 and $22.70.
Represents the weighted average price. These shares were purchased in multiple transactions at prices ranging from $22.69 and $23.00.
Represents the weighted average price. These shares were purchased in multiple transactions at prices ranging from $23.02 and $23.25.
Represents the weighted average price. These shares were purchased in multiple transactions at prices ranging from $24.82 and $25.00.