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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1609727	Synthorx Inc.	THOR	()	4

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1384859	Peter Kolchinsky	C/O Ra Capital Management, Llc 20 Park Plaza, Suite 1200 Boston MA 02116		Yes	No	Yes	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2018-12-11	1,525,235	$0.00	1,525,235	No	4	C	Indirect	See Footnote
Common Stock	Acquisiton	2018-12-11	3,653,908	$0.00	5,179,143	No	4	C	Indirect	See Footnote
Common Stock	Acquisiton	2018-12-11	4,545,455	$11.00	9,724,598	No	4	P	Indirect	See Footnote

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	C	Indirect	See Footnote
No	4	C	Indirect	See Footnote
No	4	P	Indirect	See Footnote

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Series B Preferred Stock	Disposition	2018-12-11	2,443,794	$0.00	1,525,235	$0.00
Common Stock	Series C Preferred Stock	Disposition	2018-12-11	5,854,439	$0.00	3,653,908	$0.00

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
0			No	4	C	Indirect
0			No	4	C	Indirect

Footnotes

Automatic conversion, in connection with the Issuer's initial public offering, of preferred stock into shares of common stock on a 1.60224-to-1 basis.
The shares are held as follows: 1,245,659 shares held by RA Capital Healthcare Fund, L.P. (the "Fund") and 279,576 shares held by a separately managed account (the "Account").
RA Capital Management, LLC (the "Adviser") is the general partner of the Fund and the investment adviser for the Account. Peter Kolchinsky is the sole manager of the Adviser. The Adviser is a registered investment adviser, and Dr. Kolchinsky disclaims beneficial ownership of the reported securities for purposes of Rule 16a-1(a)(1) under the Securities Exchange Act of 1934 (the "Exchange Act") in reliance on Rule 16a-1(a)(1)(vii). Dr. Kolchinsky also disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a)(2) under the Exchange Act except to the extent of his pecuniary interest therein.
The shares are held as follows: 2,941,397 shares held by the Fund and 712,511 shares held by the Account.
The shares were purchased at the Issuer's initial public offering.
These securities include 7,968,645 shares held by the Fund and 1,755,953 shares held by the Account.