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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1178670	Alnylam Pharmaceuticals Inc.	ALNY	Pharmaceutical Preparations (2834)	770602661

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1180432	John Maraganore	300 Third Street Cambridge MA 02142	Chief Executive Officer	Yes	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2018-07-25	50,000	$21.35	201,297	No	4	M	Direct
Common Stock	Disposition	2018-07-25	2,000	$102.51	199,297	No	4	S	Direct
Common Stock	Disposition	2018-07-25	3,847	$103.69	195,450	No	4	S	Direct
Common Stock	Disposition	2018-07-25	7,758	$104.83	187,692	No	4	S	Direct
Common Stock	Disposition	2018-07-25	34,995	$105.83	152,697	No	4	S	Direct
Common Stock	Disposition	2018-07-25	1,400	$106.25	151,297	No	4	S	Direct
Common Stock	Acquisiton	2018-04-16	30	$0.00	2,990	No	5	J	Indirect	by Managed Account
Common Stock	Acquisiton	2018-07-10	31	$0.00	3,021	No	5	J	Indirect	by Managed Account

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	5	J	Indirect	by Managed Account
No	5	J	Indirect	by Managed Account

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (right to buy)	Disposition	2018-07-25	50,000	$0.00	50,000	$21.35

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
98,636		2018-12-08	No	4	M	Direct

Footnotes

All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 16, 2018. The 50,000 options exercised and sold by the reporting person were due to expire on December 8, 2018.
Sale prices ranged from $101.99 to $102.94.
Sale prices ranged from $103.10 to $104.04.
Sale prices ranged from $104.17 to $105.15.
Sale prices ranged from $105.17 to $106.13.
Sale prices ranged from $106.18 to $106.33.
Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.
The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.