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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1674365	Aptinyx Inc.	APTX	Pharmaceutical Preparations (2834)	474626057

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1741434	Ashish Khanna	C/O Aptinyx Inc. 909 Davis Street, Suite 600 Evanston IL 60201	Cfo And Cbo	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2018-06-25	5,290	$0.00	256,990	No	4	C	Direct
Common Stock	Acquisiton	2018-06-25	6,046	$0.00	263,036	No	4	C	Direct
Common Stock	Acquisiton	2018-06-25	4,094	$0.00	267,130	No	4	C	Direct
Common Stock	Acquisiton	2018-06-25	6,000	$16.00	273,130	No	4	P	Direct
Common Stock	Acquisiton	2018-06-25	1,800	$16.00	1,800	No	4	P	Indirect	By family member

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	C	Direct
No	4	C	Direct
No	4	C	Direct
No	4	P	Direct
No	4	P	Indirect	By family member

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Series A-1 Convertible Preferred Stock	Disposition	2018-06-25	145,935	$0.00	5,290	$0.00
Common Stock	Series A-2 Convertible Preferred Stock	Disposition	2018-06-25	166,782	$0.00	6,046	$0.00
Common Stock	Series B Convertible Preferred Stock	Disposition	2018-06-25	112,959	$0.00	4,094	$0.00

Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
No	4	C	Direct
No	4	C	Direct
No	4	C	Direct

Footnotes

Each share of Series A-1 Convertible Preferred Stock, Series A-2 Convertible Preferred Stock and Series B Convertible Preferred Stock automatically converted into shares of Common Stock on a 27.58621-for-one basis immediately prior to the closing of the Issuer's initial public offering without payment or consideration. The shares of Series A-1 Convertible Preferred Stock, Series A-2 Convertible Preferred Stock and Series B Convertible Preferred Stock had no expiration date.
On June 25, 2018, the Reporting Person purchased 6,000 shares of common stock of the Issuer at a price of $16.00 per share pursuant to an underwritten public offering.
On June 25, 2018, a family member of the Reporting Person purchased 1,800 shares of common stock of the Issuer at a price of $16.00 per share pursuant to an underwritten public offering.