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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1610876	Jeffrey Chodakewitz	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Evp Gmda, Cmo	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2017-10-16	1,718	$96.87	116,142	No	4	M	Direct
Common Stock	Disposition	2017-10-16	300	$153.42	115,842	No	4	S	Direct
Common Stock	Disposition	2017-10-16	818	$154.76	115,024	No	4	S	Direct
Common Stock	Disposition	2017-10-16	300	$155.92	114,724	No	4	S	Direct
Common Stock	Disposition	2017-10-16	300	$157.38	114,424	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (Right to Buy)	Disposition	2017-10-16	1,718	$0.00	1,718	$96.87

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
5,157		2024-07-14	No	4	M	Direct

Footnotes

Transaction made pursuant to Dr. Chodakewitz's company-approved trading plan under Rule 10b5-1.
Dr. Chodakewitz undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $153.42 (range $153.11 to $153.58).
Open market sales reported on this line occurred at a weighted average price of $154.76 (range $154.50 to $155.15).
The option vests in 16 quarterly installments from 7/15/2014.