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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1197023	S Joshua Boger	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210		Yes	No	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2016-09-14	6,500	$36.30	274,725	No	4	M	Direct
Common Stock	Disposition	2016-09-14	400	$88.76	274,325	No	4	S	Direct
Common Stock	Disposition	2016-09-14	3,500	$89.80	270,825	No	4	S	Direct
Common Stock	Disposition	2016-09-14	200	$90.27	270,625	No	4	S	Direct
Common Stock	Disposition	2016-09-14	700	$96.20	269,925	No	4	S	Direct
Common Stock	Disposition	2016-09-14	1,700	$97.17	268,225	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (Right to Buy)	Disposition	2016-09-14	6,500	$0.00	6,500	$36.30

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
112,000		2017-01-23	No	4	M	Direct

Reported Non-Derivative Holdings

Sec. Name	Remaning Holdings	Nature of Ownership	Explanation
Common Stock	13,286	Indirect	401(k)
Common Stock	78,200	Indirect	Common Stock Held In Trust

Footnotes

Transaction made pursuant to Dr. Boger's company approved trading plan under Rule 10b5-1.
Dr. Boger undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $88.76 (range $88.22 to $88.99).
Open market sales reported on this line occurred at a weighted average price of $89.80 (range $89.26 to $90.20).
Open market sales reported on this line occurred at a weighted average price of $90.27 (range $90.26 to $90.28).
Open market sales reported on this line occurred at a weighted average price of $96.20 (range $95.78 to $96.72).
Open market sales reported on this line occurred at a weighted average price of $97.17 (range $96.83 to $97.71).
Fully vested.