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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1571498	Epizyme Inc.	EPZM	Pharmaceutical Preparations (2834)	261349956

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1632720	E. Andrew Singer	C/O Epizyme, Inc. 400 Technology Square Cambridge MA 02139	Evp & Cfo	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock, Par Value $0.0001	Acquisiton	2016-04-11	1,682	$0.00	20,489	No	4	M	Direct
Common Stock, Par Value $0.0001	Acquisiton	2016-04-11	777	$0.00	21,266	No	4	M	Direct
Common Stock, Par Value $0.0001	Disposition	2016-04-11	840	$12.48	20,426	No	4	S	Direct
Common Stock, Par Value $0.0001	Disposition	2016-04-12	173	$12.14	20,253	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Restricted Stock Units	Disposition	2016-04-11	1,682	$0.00	1,682	$0.00
Common Stock	Restricted Stock Units	Disposition	2016-04-12	777	$0.00	777	$0.00

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
57,185			No	4	M	Direct
26,430			No	4	M	Direct

Footnotes

Each restricted stock unit represents the contingent right to receive one share of Epizyme, Inc. common stock upon vesting.
The sale reported on this Form 4 was effected pursuant to a Rule 10b5-1 plan adopted by the Reporting Person to cover taxes associated with the vesting of his restricted stock.
This award, granted on February 9, 2016, pursuant to the Company's 2013 Stock Incentive plan, vests as to 25% of the total award on February 9, 2016, a year from the commencement of employment, with the remaining 75% vesting in 36 substantially equal monthly installments thereafter. Vested shares will be delivered to the reporting person.
This award, granted on February 9, 2015, pursuant to the Company's 2013 Stock Inventive Plan, vests as to 25% of the total award on February 9, 2016, with the remaining 75% vesting in 36 substantially equal monthly installments thereafter. Vested shares will be delivered to the reporting person.