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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1334365	Yuchun Lee	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210		Yes	No	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2015-12-01	1,333	$57.27	1,958	No	4	M	Direct
Common Stock	Disposition	2015-12-01	400	$128.77	1,558	No	4	S	Direct
Common Stock	Disposition	2015-12-01	625	$129.97	933	No	4	S	Direct
Common Stock	Disposition	2015-12-01	100	$131.21	833	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (right to buy)	Disposition	2015-12-01	1,333	$0.00	1,333	$57.27

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
24,667		2022-09-13	No	4	M	Direct

Footnotes

Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1.
Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $128.77 (range $128.37 to $129.09).
Open market sales reported on this line occurred at a weighted average price of $129.97 (range $129.64 to $130.60).
The option vests in 16 quarterly installments from 09/14/2012.