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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1178670	Alnylam Pharmaceuticals Inc.	ALNY	Pharmaceutical Preparations (2834)	770602661

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1192603	P Kevin Starr	300 Third Street Cambridge MA 02142		Yes	No	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2015-11-11	25,000	$9.30	25,000	No	4	M	Direct
Common Stock	Acquisiton	2015-11-11	12,500	$11.33	37,500	No	4	M	Direct
Common Stock	Disposition	2015-11-11	2,274	$105.31	35,226	No	4	S	Direct
Common Stock	Disposition	2015-11-11	4,027	$106.46	31,199	No	4	S	Direct
Common Stock	Disposition	2015-11-11	12,606	$107.39	18,593	No	4	S	Direct
Common Stock	Disposition	2015-11-11	15,499	$108.23	3,094	No	4	S	Direct
Common Stock	Disposition	2015-11-11	3,094	$109.14	0	No	4	S	Direct
Common Stock	Acquisiton	2015-11-12	12,500	$11.33	12,500	No	4	M	Direct
Common Stock	Acquisiton	2015-11-12	25,000	$15.82	37,500	No	4	M	Direct
Common Stock	Disposition	2015-11-12	35,400	$100.01	2,100	No	4	S	Direct
Common Stock	Disposition	2015-11-12	1,200	$101.58	900	No	4	S	Direct
Common Stock	Disposition	2015-11-12	900	$103.01	0	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	M	Direct
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (right to buy)	Disposition	2015-11-11	12,500	$0.00	12,500	$11.33
Common Stock	Stock Option (right to buy)	Disposition	2015-11-12	12,500	$0.00	12,500	$11.33
Common Stock	Stock Option (right to buy)	Disposition	2015-11-12	25,000	$0.00	25,000	$15.82
Common Stock	Stock Option (right to buy)	Disposition	2015-11-11	25,000	$0.00	25,000	$9.30

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
12,500	2013-06-21	2022-06-21	No	4	M	Direct
0	2013-06-21	2022-06-21	No	4	M	Direct
0	2011-06-02	2020-06-02	No	4	M	Direct
0	2012-06-09	2021-06-09	No	4	M	Direct

Footnotes

The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 2, 2015.
Sale prices ranged from $104.85 to $105.70.
Sale prices ranged from $105.86 to $106.85.
Sale prices ranged from $106.88 to $107.875.
Sale prices ranged from $107.88 to $108.81.
Sale prices ranged from $108.92 to $109.62.
Sale prices ranged from $100.00 to $100.85.
Sale prices ranged from $101.02 to $101.92.
Sale prices ranged from $102.67 to $103.44.
The option vested, in full, on the first anniversary of the Grant Date.