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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1113481	Medicines Co	MDCO	Pharmaceutical Preparations (2834)	043324394

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1204787	Clive Meanwell	8 Sylvan Way Parsippany NJ 07054	Chairman & Ceo	Yes	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2015-03-23	16,667	$18.27	341,143	No	4	M	Direct
Common Stock	Disposition	2015-03-23	16,667	$30.62	324,476	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	M	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (right-to-buy)	Disposition	2015-03-23	16,667	$0.00	16,667	$18.27

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
133,333		2015-11-30	No	4	M	Direct

Footnotes

Sales were effected pursuant to a Rule 10b5-1 program adopted by Dr. Meanwell.
Represents the weighted average sales price of the shares sold ranging from a low of $30.46 to a high of $30.8995 per share. The undersigned undertakes, upon request by the Commission staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.
This option vested in forty-eight equal installments beginning on December 30, 2005.
Not applicable.