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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1178670	Alnylam Pharmaceuticals Inc.	ALNY	Pharmaceutical Preparations (2834)	770602661

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1180432	John Maraganore	C/O Alnylam Pharmaceuticals, Inc. 300 Third Street Cambridge MA 02142	Chief Executive Officer	Yes	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Disposition	2014-05-23	1,700	$0.00	104,620	No	5	G	Direct
Common Stock	Acquisiton	2014-09-17	56,834	$7.47	161,454	No	4	M	Direct
Common Stock	Disposition	2014-09-17	3,400	$74.74	158,054	No	4	S	Direct
Common Stock	Disposition	2014-09-17	13,899	$75.65	144,155	No	4	S	Direct
Common Stock	Disposition	2014-09-17	23,286	$76.54	120,869	No	4	S	Direct
Common Stock	Disposition	2014-09-17	15,849	$77.71	105,020	No	4	S	Direct
Common Stock	Disposition	2014-09-17	400	$78.10	104,620	No	4	S	Direct
Common Stock	Acquisiton	2014-09-18	56,834	$7.47	161,454	No	4	M	Direct
Common Stock	Disposition	2014-09-18	18,962	$78.12	142,492	No	4	S	Direct
Common Stock	Disposition	2014-09-18	37,872	$79.23	104,620	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	5	G	Direct
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (Right to Buy)	Disposition	2014-09-17	56,834	$0.00	56,834	$7.47
Common Stock	Stock Option (Right to Buy)	Disposition	2014-09-18	56,834	$0.00	56,834	$7.47

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
56,834	2005-12-21	2014-12-21	No	4	M	Direct
0	2005-12-21	2014-12-21	No	4	M	Direct

Reported Non-Derivative Holdings

Sec. Name	Remaning Holdings	Nature of Ownership	Explanation
Common Stock	2,689	Indirect	By Managed Account

Footnotes

The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 19, 2014. The options exercised and sold by the Reporting Person were due to expire on December 21, 2014.
Sale prices ranged from $74.08 to $75.06.
Sale prices ranged from $75.11 to $76.06.
Sale prices ranged from $76.11 to $77.03.
Sale prices ranged from $77.08 to $78.075.
Sale prices ranged from $78.09 to $78.12.
Sale prices ranged from $77.77 to $78.76.
Sale prices ranged from $78.78 to $79.71.
The Reporting Person owns 2,689 shares of ALNY common stock under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.