Filing Details

Accession Number:
0000874015-10-000029
Form Type:
4
Zero Holdings:
No
Publication Time:
2010-12-29 19:22:53
Reporting Period:
2010-12-27
Filing Date:
2010-12-29
Accepted Time:
2010-12-29 19:22:53
SEC Url:
Form 4 Filing
Issuer
Cik Name Symbol Sector (SIC) IRS No
874015 Isis Pharmaceuticals Inc ISIS Pharmaceutical Preparations (2834) 330336973
Insiders
Cik Name Reported Address Insider Title Director Officer Large Shareholder Other
897667 T Stanley Crooke C/O Isis Pharmaceuticals, Inc.
1896 Rutherford Road
Carlsbad CA 92008
Chairman, President, Ceo Yes Yes No No
Reported Non-Derivative Transactions
Sec. Name Acquisiton - Disposition Date Amount Price Remaning Holdings Equity Swap Involved Form Type Code Nature of Ownership Explanation
Common Stock Acquisiton 2010-12-27 20,000 $9.63 20,000 No 4 M Direct
Common Stock Disposition 2010-12-27 20,000 $10.42 0 No 4 S Direct
Common Stock Acquisiton 2010-12-29 10,000 $9.63 10,000 No 4 M Direct
Common Stock Disposition 2010-12-29 10,000 $10.32 0 No 4 S Direct
Common Stock Acquisiton 2010-12-29 2,000 $9.63 2,000 No 4 M Indirect By wife
Common Stock Disposition 2010-12-29 2,000 $10.32 0 No 4 S Indirect By wife
Equity Swap Involved Form Type Code Nature of Ownership Explanation
No 4 M Direct
No 4 S Direct
No 4 M Direct
No 4 S Direct
No 4 M Indirect By wife
No 4 S Indirect By wife
Reported Derivative Transactions
Sec. Name Sec. Type Acquisiton - Disposition Date Amount Price Amount - 2 Price - 2
Common Stock Employee Stock Option (right to buy) Disposition 2010-12-27 20,000 $0.00 20,000 $9.63
Common Stock Employee Stock Option (right to buy) Disposition 2010-12-29 10,000 $0.00 10,000 $9.63
Common Stock Employee Stock Option (right to buy) Disposition 2010-12-29 2,000 $0.00 2,000 $9.63
Remaning Holdings Exercise Date Expiration Date Equity Swap Involved Transaction Form Type Transaction Code Nature of Ownership
10,000 2005-01-02 2011-01-01 No 4 M Direct
0 2005-01-02 2011-01-01 No 4 M Direct
0 2005-01-02 2011-01-01 No 4 M Indirect
Reported Non-Derivative Holdings
Sec. Name Remaning Holdings Nature of Ownership Explanation
Common Stock 875,391 Indirect By Trust
Footnotes
  1. Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/11. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on 11/10/09.
  2. The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on 11/10/09.
  3. Acquired as a result of exercising a stock option that was scheduled to expire on 1/1/11. The purchase reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person's wife on 11/10/09.
  4. The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person's wife on 11/10/09.