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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1124105	Targacept Inc	TRGT	Pharmaceutical Preparations (2834)	000000000

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1296093	P Jeffrey Brennan	C/O Targacept, Inc. 200 East First Street, Suite 300 Winston-Salem NC 27101	Svp - Bus. & Commercial Dev.	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2010-12-13	10,000	$2.93	10,000	No	4	M	Direct
Common Stock	Disposition	2010-12-13	10,000	$23.86	0	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	M	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (Right to Buy)	Disposition	2010-12-13	10,000	$0.00	10,000	$2.93

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
32,658		2019-01-08	No	4	M	Direct

Footnotes

The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $23.68 to $24.00, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
This option vested (vests) in equal installments on the last day of 16 consecutive calendar quarters beginning with March 31, 2009.