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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1571498	Epizyme Inc.	EPZM	Pharmaceutical Preparations (2834)	261349956

Insiders

Cik	Name	Reported Address	Director	Officer	Large Shareholder	Other
1288452	Bay City Capital Llc	750 Battery Street Suite 400 San Francisco CA 94111	No	No	Yes	No
1401826	Bay City Capital Fund V, L.p.	750 Battery Street Suite 400 San Francisco CA 94111	No	No	Yes	No
1409813	Bay City Capital Fund V Co-Investment Fund, L.p.	750 Battery Street Suite 400 San Francisco CA 94111	No	No	Yes	No
1461543	Bay City Capital Management V Llc	750 Battery Street Suite 400 San Francisco CA 94111	No	No	Yes	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock, Par Value $0.0001 Per Share	Disposition	2014-02-10	457,940	$29.25	3,200,789	No	4	S	Indirect	See Footnotes
Common Stock, Par Value $0.0001 Per Share	Disposition	2014-02-10	8,727	$29.25	3,192,062	No	4	S	Indirect	See Footnotes

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	S	Indirect	See Footnotes
No	4	S	Indirect	See Footnotes

Footnotes

The sale transactions reported on this Form 4 were effected as part of an underwritten public offering of common stock by Epizyme, Inc. with the Reporting Persons as selling stockholders in the offering.
Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management V LLC, a Delaware limited liability company ("Management V"), Bay City Capital Fund V, L.P., a Delaware limited partnership ("Fund V"), and Bay City Capital Fund V Co-Investment Fund, L.P., a Delaware limited partnership ("Co-Investment V"), are deemed to be a "group" for the purpose of Section 13(d) under the Securities Exchange Act of 1934. Management V is the general partner of Fund V and Co-Investment V and has sole voting and dispositive power with respect to the securities held by Fund V and Co-Investment V. BCC, the manager of Management V, is also an advisor to Fund V and Co-Investment V and has sole voting and dispositive power with respect to the securities held by Fund V and Co-Investment V.
Represent securities held by Fund V, including indirect interests of BCC and Management V. BCC and Management V each disclaims beneficial ownership with respect to these securities, except to the extent of their pecuniary interest therein.
Represent securities held by Co-Investment V, including indirect interests of BCC and Management V. BCC and Management V each disclaims beneficial ownership with respect to these securities, except to the extent of their pecuniary interest therein.