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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1113481	Medicines Co	MDCO	Pharmaceutical Preparations (2834)	043324394

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1427141	Bernard William O'connor	8 Sylvan Way Parsippany NJ 07054	Sr Vp & Chief Acct. Officer	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2014-01-10	25,000	$19.98	50,058	No	4	M	Direct
Common Stock	Acquisiton	2014-01-10	7,500	$17.04	57,558	No	4	M	Direct
Common Stock	Acquisiton	2014-01-10	15,000	$19.06	72,558	No	4	M	Direct
Common Stock	Acquisiton	2014-01-10	15,908	$19.36	88,466	No	4	M	Direct
Common Stock	Acquisiton	2014-01-10	365	$7.31	88,831	No	4	M	Direct
Common Stock	Acquisiton	2014-01-10	694	$17.45	89,525	No	4	M	Direct
Common Stock	Acquisiton	2014-01-10	7,917	$22.04	97,442	No	4	M	Direct
Common Stock	Disposition	2014-01-10	72,384	$40.00	25,058	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	M	Direct
No	4	M	Direct
No	4	M	Direct
No	4	M	Direct
No	4	M	Direct
No	4	M	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (right-to-buy)	Disposition	2014-01-10	25,000	$0.00	25,000	$19.98
Common Stock	Stock Option (right-to-buy)	Disposition	2014-01-10	7,500	$0.00	7,500	$17.04
Common Stock	Stock Option (right-to-buy)	Disposition	2014-01-10	15,000	$0.00	15,000	$19.06
Common Stock	Stock Option (right-to-buy)	Disposition	2014-01-10	15,908	$0.00	15,908	$19.36
Common Stock	Stock Option (right-to-buy)	Disposition	2014-01-10	365	$0.00	365	$7.31
Common Stock	Stock Option (right-to-buy)	Disposition	2014-01-10	694	$0.00	694	$17.45
Common Stock	Stock Option (right-to-buy)	Disposition	2014-01-10	7,917	$0.00	7,917	$22.04

Remaning Holdings	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
25,000	2016-04-24	No	4	M	Direct
0	2017-07-12	No	4	M	Direct
15,000	2017-10-15	No	4	M	Direct
15,907	2018-02-15	No	4	M	Direct
1,823	2020-02-19	No	4	M	Direct
11,805	2021-02-18	No	4	M	Direct
12,083	2022-02-24	No	4	M	Direct

Footnotes

The common stock sales were effected pursuant to a Rule 10b5-1 program adopted by the reporting person on March 15, 2013.
This option vested in forty-eight equal monthly installments ending April 12, 2010.
This option vested in forty-eight equal monthly installments ending July 12, 2011.
This option vested in forty-eight equal monthly installments ending October 15, 2011.
This option vested in forty-eight equal monthly installments beginning March 15, 2008.
This option vests in forty-eight equal monthly installments beginning March 19, 2010.
This option vests in forty-eight equal monthly installments beginning March 18, 2011.
This option vests in forty-eight equal monthly installments beginning March 24, 2012.
Not applicable.