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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1356857	Trius Therapeutics Inc	TSRX	Pharmaceutical Preparations (2834)	201320630

Insiders

Cik	Name	Reported Address	Director	Officer	Large Shareholder	Other
1245624	James Healy	140 Geary Street, 10Th Floor San Francisco CA 94108	No	No	Yes	No
1362314	Eric Buatois	140 Geary Street, 10Th Floor San Francisco CA 94108	No	No	Yes	No
1380734	P L Vii Partners Venture Sofinnova	140 Geary Street 10Th Floor San Francisco CA 94108	No	No	Yes	No
1421501	Sofinnova Management Vii, L.l.c.	140 Geary Street, 10Th Floor San Francisco CA 94108	No	No	Yes	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2010-08-06	1,892,177	$0.00	1,892,177	No	4	C	Direct
Common Stock	Acquisiton	2010-08-06	893,395	$4.38	2,785,572	No	4	C	Direct
Common Stock	Acquisiton	2010-08-06	830,000	$5.00	3,615,572	No	4	P	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	C	Direct
No	4	C	Direct
No	4	P	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Series A-2 Convertible Preferred Stock	Disposition	2010-08-06	10,909,092	$0.00	10,909,092	$0.00
Common Stock	Series B Convertible Preferred Stock	Disposition	2010-08-06	5,363,636	$0.00	5,363,636	$0.00

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
0			No	4	C	Direct
0			No	4	C	Direct

Footnotes

Upon the closing of the Issuer's initial public offering, each 8.6 shares of the Series A-2 Convertible Preferred Stock and Series B Convertible Preferred Stock automatically converted into one share of Common Stock, and had no expiration date.
Shares are held by Sofinnova Venture Partners VII, L.P. ("SV VII"). Sofinnova Management VII, L.L.C ("SV VII LLC") is the general partner of SV VII, and Michael F. Powell, a director of the issuer, James I. Healy and Eric P. Buatois, the managing general partners of SV VII, LLC, may be deemed to share voting and dispositive power over the shares held by SV VII. Such persons disclaim beneficial ownership of shares held by SV VII except to the extent of any pecuniary interest therein.
The Common Stock was acquired upon conversion of a Secured Convertible Promissory Note exempt from the definition of a derivative security and whose conversion ratio did not become fixed until automatic conversion at the time of the closing of the Issuer's initial public offering.
The shares were purchased in the Issuer's initial public offering.
Transaction lines included in amendment to gain access to the filing system. Reporting Persons on Exhibit 99.1 were inadvertently omitted from the previous filing, and this report is being amended to reflect a joint/group filing.