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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1197032	F Ian Smith	C/O Vertex Pharmaceuticals Incorporated 130 Waverly Street Cambridge MA 02139	Evp & Cfo	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Disposition	2010-05-07	5,869	$35.72	49,008	No	4	S	Direct
Common Stock	Disposition	2010-05-07	9,131	$36.16	39,877	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	S	Direct
No	4	S	Direct

Reported Non-Derivative Holdings

Sec. Name	Remaning Holdings	Nature of Ownership	Explanation
Common Stock	4,401	Indirect	401(k)

Footnotes

Transaction made pursuant to Mr. Smith's company approved trading plan established under Rule 10b5-1.
Open market sales reported on this line occurred at a weighted average price of $35.72 (range $35.06 to $35.99).
Open market sales reported on this line occurred at a weighted average price of $36.16 (range $36.00 to $36.50).
Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.