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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1113481	Medicines Co	MDCO	Pharmaceutical Preparations (2834)	043324394

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1318459	Michael Paul Antinori	8 Sylvan Way Parsippany NJ 07054	Sr. Vp & General Counsel	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Commmon Stock	Acquisiton	2013-09-13	23,500	$28.02	75,406	No	4	M	Direct
Common Stock	Acquisiton	2013-09-13	50,000	$28.60	125,406	No	4	M	Direct
Common Stock	Disposition	2013-09-13	73,500	$34.50	51,906	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	M	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Option (Right-to-Buy)	Disposition	2013-09-13	23,500	$0.00	23,500	$28.02
Common Stock	Option (Right-to-Buy)	Disposition	2013-09-13	50,000	$0.00	50,000	$28.60

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
0		2014-12-14	No	4	M	Direct
0		2017-02-16	No	4	M	Direct

Footnotes

The common stock sales reported on this line of the Form 4 were effected pursuant to a Rule 10b5-1 program adopted by Mr. Antinori on May 9, 2013.
As of September 13, 2013, the original grant (23,500 shares granted on December 14, 2004) was fully vested. After the exercise of the options reported hereby, all shares covered by this option have been exercised.
As of September 13, 2013, the original grant (50,000 shares granted on February 16, 2007) was fully vested. After the exercise of the options reported hereby, all shares covered by this option have been exercised.