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Filing Details

Accession Number:: 0000947871-12-000779
Form Type:: 4
Zero Holdings:: No
Publication Time:: 2012-12-19 21:42:40
Reporting Period:: 2012-12-17

Filing Date:: 2012-12-19
Accepted Time:: 2012-12-19 21:42:40
SEC Url:: Form 4 Filing

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1356576	Supernus Pharmaceuticals Inc	SUPN	Pharmaceutical Preparations (2834)	000000000

Insiders

Cik	Name	Reported Address	Director	Officer	Large Shareholder	Other
1055949	D Samuel Isaly	601 Lexington Avenue 54Th Floor New York NY 10022	No	No	Yes	No
1055951	Orbimed Advisors Llc	601 Lexington Avenue 54Th Floor New York NY 10022	No	No	Yes	No
1281668	Orbimed Capital Gp Ii Llc	601 Lexington Avenue 54Th Floor New York NY 10022	No	No	Yes	No

Reported Non-Derivative Transactions

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Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Disposition	2012-12-17	197,815	$6.85	100,000	No	4	S	Indirect	See Footnotes
Common Stock	Disposition	2012-12-18	100,000	$7.08	0	No	4	S	Indirect	See Footnotes

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	S	Indirect	See Footnotes
No	4	S	Indirect	See Footnotes

Reported Non-Derivative Holdings

Sec. Name	Remaning Holdings	Nature of Ownership	Explanation
Common Stock	2,402,600	Indirect	See Footnotes
Common Stock	899,583	Indirect	See Footnotes

Footnotes

This price reported in Column 4 is a weighted average price. The reported shares were sold in multiple transactions at prices ranging from $6.79 to $7.32, inclusive. Upon request, the Reporting Persons undertake to provide the Issuer, any security holder of the Issuer, or the Securities and Exchange Commission, full information regarding the shares sold at each separate price within the ranges set forth in footnote (1) of this Form 4.
This price reported in Column 4 is a weighted average price. The reported shares were sold in multiple transactions at prices ranging from $6.83 to $7.51, inclusive. Upon request, the Reporting Persons undertake to provide the Issuer, any security holder of the Issuer, or the Securities and Exchange Commission, full information regarding the shares sold at each separate price within the ranges set forth in footnote (2) of this Form 4.
The Shares reported herein are directly owned by UBS Juniper Crossover Fund, L.L.C. ("Juniper"). OrbiMed Advisors LLC ("Advisors"), a registered adviser under the Investment Advisers Act of 1940, as amended, manages the portfolio of Juniper and may be deemed to have beneficial ownership of Shares held by Juniper by virtue of that relationship. Mr. Samuel D. Isaly ("Isaly"), a natural person, may be deemed to have beneficial ownership of such Shares in his capacity as the managing member of, and holder of a controlling interest, in Advisors.
These Shares are beneficially owned by OrbiMed Private Investments II, LP ("OP II"). OrbiMed Capital GP II LLC ("GP II") is the general partner of OPI II. Advisors is the managing member of GP II. Advisors and GP II may be deemed to have beneficial ownership of Shares held by OPI II by virtue of such relationships. Isaly, a natural person, may be deemed to have beneficial ownership of such Shares in his capacity as the managing member of, and holder of a controlling interest, in Advisors.
These Shares are beneficially owned by OrbiMed Private Investments II (QP), LP ("OPI II QP"). GP II is the general partner of OPI II QP. Advisors is the managing member of GP II. Advisors and GP II may be deemed to have beneficial ownership of Shares held by OPI II QP by virtue of such relationships. Isaly may be deemed to have beneficial ownership of such Shares in his capacity as the managing member of, and holder of a controlling interest, in Advisors.
Each of Advisors, Isaly and GP II disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its or his pecuniary interest therein, if any. This report shall not be deemed an admission that the Reporting Persons are beneficial owners for the purpose of Section 16 of the Exchange Act, or for any other purpose.
No transaction has been made with respect to the Shares listed in this row.