Filing Details
- Accession Number:
- 0001193805-18-000983
- Form Type:
- 13G Filing
- Publication Date:
- 2018-07-17 11:25:14
- Filed By:
- Flynn James E
- Company:
- Mannkind Corp (NASDAQ:MNKD)
- Filing Date:
- 2018-07-17
- SEC Url:
- 13G Filing
Please notice the below summary table is generated without human intervention and may contain errors. Please refer to the complete filing displayed below for exact figures.
Name | Sole Voting Power | Shared Voting Power | Sole Dispositive Power | Shared Dispositive Power | Aggregate Amount Owned Power | Percent of Class |
---|---|---|---|---|---|---|
Deerfield Mgmt | 0 | 14,576,376 | 0 | 14,576,376 | 14,576,376 | 9.985% |
Deerfield Management Company | 0 | 14,576,376 | 0 | 14,576,376 | 14,576,376 | 9.985% |
Deerfield Private Design Fund II | 0 | 9,863,092 | 0 | 9,863,092 | 9,863,092 | 6.77% |
Deerfield Private Design International II | 0 | 10,463,284 | 0 | 10,463,284 | 10,463,284 | 7.18% |
James E. Flynn | 0 | 14,576,376 | 0 | 14,576,376 | 14,576,376 | 9.985% |
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549
SCHEDULE 13G
(Rule 13d-102)
INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED
PURSUANT TO RULE 13d-2(b)
(Amendment No. )*
MannKind Corporation
(Name of Issuer)
Common Stock
(Title of Class of Securities)
56400P706
(CUSIP Number)
January 18, 2018
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
☐ Rule 13d-1(b)
☒ Rule 13d-1(c)
☐ Rule 13d-1(d)
(Page 1 of 10 Pages)
----------
* The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).
Explanatory Note: As previously disclosed by the Issuer, on January 18, 2018, the Issuer, Deerfield Private Design Fund II, L.P. (“DPD II”) and Deerfield Private Design International II, L.P (“DPDI II” and, together with DPD II, the “Funds”) amended the terms of convertible notes held by the Funds (i) to increase the number of shares of the Issuer’s common stock constituting the Conversion Cap (as defined below) thereunder to 10,000,000 shares and (ii) to reduce the minimum conversion price (the “Floor Price”) applicable to the conversion of principal amounts under such convertible notes into shares of the Issuer’s common stock. Such amendment resulted in the Reporting Persons becoming the beneficial owners of more than 5% of the Issuer’s common stock. Subsequently, on July 12, 2018, the Conversion Cap was reduced to 5,750,000 shares of common stock and the Floor Price was further reduced.
CUSIP No. | 56400P706 | 13G | Page 2 of 10 Pages |
1. | NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
Deerfield Mgmt, L.P. | ||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
| (a) ☐ (b) ☒ | |
3. | SEC USE ONLY
| ||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware | ||
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH | 5. | SOLE VOTING POWER
0 | |
6. | SHARED VOTING POWER
14,576,376 (1) | ||
7.
| SOLE DISPOSITIVE POWER
0 | ||
8.
| SHARED DISPOSITIVE POWER
14,576,376 (1) | ||
9.
| AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
14,576,376 (1) | ||
10. | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
| ☐ | |
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
9.985% (1) | ||
12. | TYPE OF REPORTING PERSON*
PN |
(1) Comprised of an aggregate of 8,826,376 shares of common stock and 5,750,000 shares of common stock underlying convertible notes held by Deerfield Private Design Fund II, L.P. and Deerfield Private Design International II, L.P., of which Deerfield Mgmt, L.P. is the general partner. The provisions of the convertible notes prohibit the issuance of shares of common stock upon conversion of the notes if the issuance of such shares together with any previous issuance of common stock under the convertible notes from and after July 12, 2018 would exceed 5,750,000 shares (the “Conversion Cap”). The number of shares reported excludes shares issuable upon conversion of the convertible notes in excess of the Conversion Cap. In addition, the convertible notes restrict the conversion of such securities to the extent that, upon such conversion, the number of shares then beneficially owned by the holder and its affiliates and any other person or entities with which such holder would constitute a Section 13(d) “group” would exceed 9.985% of the total number of shares of the Issuer then outstanding (the “Ownership Cap”). Accordingly, notwithstanding the number of shares reported, the reporting person disclaims beneficial ownership of the shares of common stock issuable upon conversion of such convertible notes to the extent that upon such conversion the number of shares of common stock beneficially owned by all reporting persons hereunder, in the aggregate, would exceed the Ownership Cap.
CUSIP No. | 56400P706 | 13G | Page 3 of 10 Pages |
1. | NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
Deerfield Management Company, L.P. | ||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
| (a) ☐ (b) ☒ | |
3. | SEC USE ONLY
| ||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware | ||
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH | 5. | SOLE VOTING POWER
0 | |
6. | SHARED VOTING POWER
14,576,376 (2) | ||
7.
| SOLE DISPOSITIVE POWER
0 | ||
8.
| SHARED DISPOSITIVE POWER
14,576,376 (2) | ||
9.
| AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
14,576,376 (2) | ||
10. | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
| ☐ | |
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
9.985% (2) | ||
12. | TYPE OF REPORTING PERSON*
PN |
(2) Comprised of an aggregate of 8,826,376 shares of common stock and 5,750,000 shares of common stock underlying convertible notes held by Deerfield Private Design Fund II, L.P. and Deerfield Private Design International II, L.P., of which Deerfield Management Company, L.P. is the investment advisor. The provisions of the convertible notes prohibit the issuance of shares of common stock upon conversion of the notes if the issuance of such shares together with any previous issuance of common stock under the convertible notes from and after July 12, 2018 would exceed 5,750,000 shares (the “Conversion Cap”). The number of shares reported excludes shares issuable upon conversion of the convertible notes in excess of the Conversion Cap. In addition, the convertible notes restrict the conversion of such securities to the extent that, upon such conversion, the number of shares then beneficially owned by the holder and its affiliates and any other person or entities with which such holder would constitute a Section 13(d) “group” would exceed 9.985% of the total number of shares of the Issuer then outstanding (the “Ownership Cap”). Accordingly, notwithstanding the number of shares reported, the reporting person disclaims beneficial ownership of the shares of common stock issuable upon conversion of such convertible notes to the extent that upon such conversion the number of shares of common stock beneficially owned by all reporting persons hereunder, in the aggregate, would exceed the Ownership Cap.
CUSIP No. | 56400P706 | 13G | Page 4 of 10 Pages |
1. | NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
Deerfield Private Design Fund II, L.P. | ||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
| (a) ☐ (b) ☒ | |
3. | SEC USE ONLY
| ||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware | ||
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH | 5. | SOLE VOTING POWER
0 | |
6. | SHARED VOTING POWER
9,863,092 (3) | ||
7.
| SOLE DISPOSITIVE POWER
0 | ||
8.
| SHARED DISPOSITIVE POWER
9,863,092 (3) | ||
9.
| AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9,863,092 (3) | ||
10. | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
| ☐ | |
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
6.77% (3) | ||
12. | TYPE OF REPORTING PERSON*
PN |
(3) Comprised of an aggregate of 4,113,092 shares of common stock and 5,750,000 shares of common stock underlying convertible notes. The provisions of the convertible notes prohibit the issuance of shares of common stock upon conversion of the notes if the issuance of such shares together with any previous issuance of common stock under the convertible notes from and after July 12, 2018 would exceed 5,750,000 shares (the “Conversion Cap”). The number of shares reported excludes shares issuable upon conversion of the convertible notes in excess of the Conversion Cap. In addition, the convertible notes restrict the conversion of such securities to the extent that, upon such conversion, the number of shares then beneficially owned by the holder and its affiliates and any other person or entities with which such holder would constitute a Section 13(d) “group” would exceed 9.985% of the total number of shares of the Issuer then outstanding (the “Ownership Cap”). Accordingly, notwithstanding the number of shares reported, the reporting person disclaims beneficial ownership of the shares of common stock issuable upon conversion of such convertible notes to the extent that upon such conversion the number of shares of common stock beneficially owned by all reporting persons hereunder, in the aggregate, would exceed the Ownership Cap.
CUSIP No. | 56400P706 | 13G | Page 5 of 10 Pages |
1. | NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
Deerfield Private Design International II, L.P. | ||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
| (a) ☐ (b) ☒ | |
3. | SEC USE ONLY
| ||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION
British Virgin Islands | ||
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH | 5. | SOLE VOTING POWER
0 | |
6. | SHARED VOTING POWER
10,463,284 (4) | ||
7.
| SOLE DISPOSITIVE POWER
0 | ||
8.
| SHARED DISPOSITIVE POWER
10,463,284 (4) | ||
9.
| AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
10,463,284 (4) | ||
10. | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
| ☐ | |
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
7.18% (4) | ||
12. | TYPE OF REPORTING PERSON*
PN |
(4) Comprised of 4,713,284 shares of common stock and 5,750,000 shares of common stock underlying convertible notes. The provisions of the convertible notes prohibit the issuance of shares of common stock upon conversion of the notes if the issuance of such shares together with any previous issuance of common stock under the convertible notes from and after July 12, 2018 would exceed 5,750,000 shares (the “Conversion Cap”). The number of shares reported excludes shares issuable upon conversion of the convertible notes in excess of the Conversion Cap. In addition, the convertible notes restrict the conversion of such securities to the extent that, upon such conversion, the number of shares then beneficially owned by the holder and its affiliates and any other person or entities with which such holder would constitute a Section 13(d) “group” would exceed 9.985% of the total number of shares of the Issuer then outstanding (the “Ownership Cap”). Accordingly, notwithstanding the number of shares reported, the reporting person disclaims beneficial ownership of the shares of common stock issuable upon conversion of such convertible notes to the extent that upon such conversion the number of shares of common stock beneficially owned by all reporting persons hereunder, in the aggregate, would exceed the Ownership Cap.
CUSIP No. | 56400P706 | 13G | Page 6 of 10 Pages |
1. | NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
James E. Flynn | ||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
| (a) ☐ (b) ☒ | |
3. | SEC USE ONLY
| ||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION
United States | ||
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH | 5. | SOLE VOTING POWER
0 | |
6. | SHARED VOTING POWER
14,576,376 (5) | ||
7.
| SOLE DISPOSITIVE POWER
0 | ||
8.
| SHARED DISPOSITIVE POWER
14,576,376 (5) | ||
9.
| AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
14,576,376 (5) | ||
10. | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
| ☐ | |
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
9.985% (5) | ||
12. | TYPE OF REPORTING PERSON*
IN |
(5) Comprised of an aggregate of 8,826,376 shares of common stock and 5,750,000 shares of common stock underlying convertible notes held by Deerfield Private Design Fund II, L.P. and Deerfield Private Design International II, L.P. The provisions of the convertible notes prohibit the issuance of shares of common stock upon conversion of the notes if the issuance of such shares together with any previous issuance of common stock under the convertible notes from and after July 12, 2018 would exceed 5,750,000 shares (the “Conversion Cap”). The number of shares reported excludes shares issuable upon conversion of the convertible notes in excess of the Conversion Cap. In addition, the convertible notes restrict the conversion of such securities to the extent that, upon such conversion, the number of shares then beneficially owned by the holder and its affiliates and any other person or entities with which such holder would constitute a Section 13(d) “group” would exceed 9.985% of the total number of shares of the Issuer then outstanding (the “Ownership Cap”). Accordingly, notwithstanding the number of shares reported, the reporting person disclaims beneficial ownership of the shares of common stock issuable upon conversion of such convertible notes to the extent that upon such conversion the number of shares of common stock beneficially owned by all reporting persons hereunder, in the aggregate, would exceed the Ownership Cap.
CUSIP No. | 56400P706 | 13G | Page 7 of 10 Pages |
Item 1(a). | Name of Issuer: | |
MannKind Corporation | ||
Item 1(b). | Address of Issuer's Principal Executive Offices: | |
30930 Russell Ranch Road, Suite 301 Westlake Village, California 91355 | ||
Item 2(a). | Name of Person Filing: | |
James E. Flynn, Deerfield Mgmt, L.P., Deerfield Management Company, L.P., Deerfield Private Design Fund II, L.P., Deerfield Private Design International II, L.P. | ||
Item 2(b). | Address of Principal Business Office, or if None, Residence: | |
James E. Flynn, Deerfield Mgmt, L.P., Deerfield Management Company, L.P., Deerfield Private Design Fund II, L.P., Deerfield Private Design International II, L.P., 780 Third Avenue, 37th Floor, New York, NY 10017 | ||
Item 2(c). | Citizenship: | |
Deerfield Mgmt, L.P., Deerfield Management Company, L.P., Deerfield Private Design Fund II, L.P. - Delaware limited partnerships;
Deerfield Private Design International II, L.P. – British Virgin Islands limited partnership;
James E. Flynn - United States citizen | ||
Item 2(d). | Title of Class of Securities: | |
Common Stock | ||
Item 2(e). | CUSIP Number: | |
56400P706 | ||
Item 3. | If This Statement is Filed Pursuant to Rule 13d-1(b), or 13d-2(b) or (c), Check Whether the Person Filing is a: | |
(a) | ☐ | Broker or dealer registered under Section 15 of the Exchange Act. |
(b) | ☐ | Bank as defined in Section 3(a)(6) of the Exchange Act. |
(c) | ☐ | Insurance company as defined in Section 3(a)(19) of the Exchange Act. |
(d) | ☐ | Investment company registered under Section 8 of the Investment Company Act. |
(e) | ☐ | An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E); |
(f) | ☐ | An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F); |
(g) | ☐ | A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G); |
(h) | ☐ | A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act; |
(i) | ☐ | A church plan that is excluded from the definition of an investment company under Section 3(c)(14) of the Investment Company Act; |
CUSIP No. | 56400P706 | 13G | Page 8 of 10 Pages |
(j) | ☐ | A non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J); |
(k) | ☐ | Group, in accordance with Rule 13d-1(b)(1)(ii)(K). |
If filing as a non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J), please specify the type of institution: _________________
Item 4. | Ownership. | ||
Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1. | |||
(a) | Amount beneficially owned**: | ||
Deerfield Mgmt, L.P. – 14,576,376 shares Deerfield Management Company, L.P. – 14,576,376 shares Deerfield Private Design Fund II, L.P. – 9,863,092 shares Deerfield Private Design International II, L.P. – 10,463,284 shares James E. Flynn – 14,576,376 shares | |||
(b) | Percent of class**: | ||
Deerfield Mgmt, L.P. – 9.985% Deerfield Management Company, L.P. – 9.985% Deerfield Private Design Fund II, L.P. – 6.77% Deerfield Private Design International II, L.P. – 7.18% James E. Flynn – 9.985% | |||
(c) | Number of shares as to which such person has**: | ||
(i) | Sole power to vote or to direct the vote: | All Reporting Persons - 0 | |
(ii) | Shared power to vote or to direct the vote: | Deerfield Mgmt, L.P. – 14,576,376 Deerfield Management Company, L.P. – 14,576,376 Deerfield Private Design Fund II, L.P. – 9,863,092 Deerfield Private Design International II, L.P. – 10,463,284 James E. Flynn - 14,576,376 | |
(iii) | Sole power to dispose or to direct the disposition of: | All Reporting Persons - 0 | |
(iv) | Shared power to dispose or to direct the disposition of: | Deerfield Mgmt, L.P. – 14,576,376 Deerfield Management Company, L.P. – 14,576,376 Deerfield Private Design Fund II, L.P. – 9,863,092 Deerfield Private Design International II, L.P. – 10,463,284 James E. Flynn - 14,576,376 |
**See footnotes on cover pages which are incorporated by reference herein.
CUSIP No. | 56400P706 | 13G | Page 9 of 10 Pages |
Item 5. | Ownership of Five Percent or Less of a Class. |
If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities check the following ☐. | |
Item 6. | Ownership of More Than Five Percent on Behalf of Another Person. |
If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than five percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. | |
N/A | |
Item 7. | Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person. |
If a parent holding company or Control person has filed this schedule, pursuant to Rule 13d-1(b)(1)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company or control person has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. | |
N/A | |
Item 8. | Identification and Classification of Members of the Group. |
If a group has filed this schedule pursuant to ss.240.13d-1(b)(1)(ii)(J), so indicate under Item 3(j) and attach an exhibit stating the identity and Item 3 classification of each member of the group. If a group has filed this schedule pursuant to ss.240.13d-1(c) or ss.240.13d-1(d), attach an exhibit stating the identity of each member of the group. | |
See Exhibit B | |
Item 9. | Notice of Dissolution of Group. |
Notice of dissolution of a group may be furnished as an exhibit stating the date of the dissolution and that all further filings with respect to transactions in the security reported on will be filed, if required, by members of the group, in their individual capacity. See Item 5. | |
N/A | |
Item 10. | Certifications. |
"By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11." |
CUSIP No. | 56400P706 | 13G | Page 10 of 10 Pages |
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
DEERFIELD MGMT, L.P.
By: J.E. Flynn Capital, LLC, General Partner
By: /s/ Jonathan Isler
Jonathan Isler, Attorney-In-Fact
DEERFIELD MANAGEMENT COMPANY, L.P.
By: Flynn Management LLC, General Partner
By: /s/ Jonathan Isler
Jonathan Isler, Attorney-In-Fact
DEERFIELD PRIVATE DESIGN FUND II, L.P.
By: Deerfield Mgmt, L.P., General Partner
By: J.E. Flynn Capital, LLC, General Partner
By: /s/ Jonathan Isler
Jonathan Isler, Attorney-In-Fact
DEERFIELD PRIVATE DESIGN INTERNATIONAL II, L.P.
By: Deerfield Mgmt, L.P., General Partner
By: J.E. Flynn Capital, LLC, General Partner
By: /s/ Jonathan Isler
Jonathan Isler, Attorney-In-Fact
JAMES E. FLYNN
/s/ Jonathan Isler
Jonathan Isler, Attorney-In-Fact
Date: July 16, 2018
Exhibit List
Exhibit A. Joint Filing Agreement.
Exhibit B. Item 8 Statement.
Exhibit C (1). Power of Attorney.
(1) Power of Attorney previously filed as Exhibit 24 to a Form 3 with regard to Proteon Therapeutics, Inc. filed with the Securities and Exchange Commission on August 4, 2017 by Deerfield Special Situations Fund, L.P., Deerfield Partners, L.P., Deerfield International Master Fund, L.P., Deerfield Private Design Fund III, L.P., Deerfield Private Design Fund IV, L.P., Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt IV, L.P., Deerfield Management Company, L.P., and James E. Flynn.
Exhibit A
Agreement
The undersigned agree that this Schedule 13G, and all amendments thereto, relating to the Common Stock of MannKind Corporation shall be filed on behalf of the undersigned.
DEERFIELD MGMT, L.P.
By: J.E. Flynn Capital, LLC, General Partner
By: /s/ Jonathan Isler
Jonathan Isler, Attorney-In-Fact
DEERFIELD MANAGEMENT COMPANY, L.P.
By: Flynn Management LLC, General Partner
By: /s/ Jonathan Isler
Jonathan Isler, Attorney-In-Fact
DEERFIELD PRIVATE DESIGN FUND II, L.P.
By: Deerfield Mgmt, L.P., General Partner
By: J.E. Flynn Capital, LLC, General Partner
By: /s/ Jonathan Isler
Jonathan Isler, Attorney-In-Fact
DEERFIELD PRIVATE DESIGN INTERNATIONAL II, L.P.
By: Deerfield Mgmt, L.P., General Partner
By: J.E. Flynn Capital, LLC, General Partner
By: /s/ Jonathan Isler
Jonathan Isler, Attorney-In-Fact
JAMES E. FLYNN
/s/ Jonathan Isler
Jonathan Isler, Attorney-In-Fact
Exhibit B
Due to the relationships between them, the reporting persons hereunder may be deemed to constitute a “group” with one another for purposes of Section 13(d)(3) of the Securities Exchange Act of 1934.