Filing Details

	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

	SCHEDULE 13G
	Under the Securities Exchange Act of 1934
	(Amendment No. 1)*

	ContraFect Corporation
	(Name of Issuer)

	Common Stock, par value $0.0001 per share
	(Title of Class of Securities)

	212326102
	(CUSIP Number)

	December 31, 2016
	(Date of Event which Requires Filing of this Statement)

(1) Does not include additional shares of common stock issuable upon the exercise of warrants which contain a blocker provision which currently provides that the warrant may be exercised only to a point where the holder, together with its affiliates and any other person or entity acting as a group, would beneficially own a maximum of 9.99% of the Issuer’s outstanding shares of common stock (the “Blocker”). See Item 4 below.

(1) Does not include additional shares of common stock issuable upon the exercise of warrants which contain the Blocker. See Item 4 below.

(1) Does not include additional shares of common stock issuable upon the exercise of warrants which contain the Blocker. See Item 4 below.

(1) Does not include additional shares of common stock issuable upon the exercise of warrants which contain the Blocker.  See Item 4 below.

Item 1.

Item 2.

Item 3.

If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

Item 4.

Ownership***

Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

*** Shares reported herein for Cormorant Asset Management, LLC represent shares which are beneficially owned by Cormorant Global Healthcare Master Fund, LP (the “Fund”), as reported herein, and shares which are beneficially owned by a managed account (the “Account”).  Cormorant Global Healthcare GP, LLC serves as the general partner of the Fund, and Cormorant Asset Management, LLC serves as the investment manager to both the Fund and the Account.  Bihua Chen serves as the managing member of Cormorant Global Healthcare GP, LLC and Cormorant Asset Management, LLC.  Each of the Reporting Persons disclaims beneficial ownership of the shares reported herein except to the extent of its or his pecuniary interest therein.

(1) Does not include additional shares of common stock issuable upon the exercise of warrants which contain a blocker provision which currently provides that the warrant may be exercised only to a point where the holder, together with its affiliates and any other person or entity acting as a group, would beneficially own a maximum of 9.99% of the Issuer’s outstanding shares of common stock (the “Blocker”).  The Blocker may be waived by the holder of the warrant upon at least 61 days’ prior notice to the Issuer.    If not for the Blocker, the reporting persons would own in excess of 9.99% of the Issuer’s outstanding shares of common stock.  The Fund beneficially owns: 2,999,340 shares of common stock, 199,150 shares of common stock issuable upon the exercise of preferred stock, warrants (not subject to the Blocker) to purchase 99,587 shares of common stock, and warrants (subject to the Blocker) to purchase 2,494,500 shares of common stock.  The Account beneficially owns: 607,220 shares of common stock, 37,256 shares of common stock issuable upon the exercise of preferred stock, warrants (not subject to the Blocker) to purchase 18,616 shares of common stock, and warrants (subject to the Blocker) to purchase 505,500 shares of common stock.  Percentage calculations herein are based upon there being 41,578,804 issued and outstanding stock as of November 7, 2016 as reported in the Issuer’s 10Q filed with the SEC on November 9, 2016.

Item 5.  Ownership of Five Percent or Less of a Class

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following [  ].

Item 6.  Ownership of More than Five Percent on Behalf of Another Person

Not applicable.

Item 7.  Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company

Not applicable.

Item 8.

Identification and Classification of Members of the Group

Not applicable.

Item 9.

Notice of Dissolution of Group

Not applicable.

Item 10.

Certification

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this Statement is true, complete and correct.

February 14, 2017

CORMORANT GLOBAL HEALTHCARE MASTER FUND, LP

By: Cormorant Global Healthcare GP, LLC

its General Partner

By: /s/ Bihua Chen

Bihua Chen, Managing Member

CORMORANT GLOBAL HEALTHCARE GP, LLC

By: /s/ Bihua Chen

Bihua Chen, Managing Member

CORMORANT ASSET MANAGEMENT, LLC

By: /s/ Bihua Chen

Bihua Chen, Managing Member

Bihua Chen