Filing Details

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

 

SCHEDULE 13G

 

UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. )*

  

Ambrx Biopharma Inc.

(Name of Issuer)

 

Ordinary shares, par value $0.0001 per share

(Title of Class of Securities)

 

02290A102**

(CUSIP Number)

 

February 16, 2023

(Date of Event Which Requires Filing of This Statement)

 

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

 

¨

Rule 13d-1(b)

 

x

Rule 13d-1(c)

 

¨

Rule 13d-1(d)

 

*	The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.
**	There is no CUSIP number assigned to the ordinary shares. The CUSIP number 02290A102 has been assigned to the American Depositary Shares (“ADSs”) of the Issuer, which are quoted on the New York Stock Exchange under the symbol “AMAM.” Each ADS represents seven (7) ordinary shares.

 

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

 

 

CUSIP No. 02290A102

Page 2 of 17

 

1.		Name of reporting persons   Venrock Healthcare Capital Partners III, L.P.
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
3.		SEC USE ONLY
4.		Citizenship or Place of Organization   Delaware

Number of Shares Beneficially Owned by Each Reporting Person With:	5.		Sole Voting Power   0
	6.		Shared Voting Power   26,740,0002
	7.		Sole Dispositive Power   0
	8.		Shared Dispositive Power   26,740,0002

9.		Aggregate Amount Beneficially Owned by Each Reporting Person   26,740,0002
10.		Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
11.		Percent of Class Represented by Amount in Row (9)   9.9%3
12.		Type of Reporting Person (See Instructions)   PN

 

1	Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G.

 

2

Consists of (i) 7,029,946 ordinary shares in the form of 1,004,278 American Depositary Shares (“ADSs”) held by Venrock Healthcare Capital Partners III, L.P., (ii) 703,262 ordinary shares in the form of 100,466 ADSs held by VHCP Co-Investment Holdings III, LLC and (iii) 19,006,792 ordinary shares in the form of 2,715,256 ADSs held by Venrock Healthcare Capital Partners EG, L.P. Each ADS represents seven (7) ordinary shares.

 

3	This percentage is calculated based upon 270,328,483 ordinary shares (including in the form of ADSs) outstanding as of June 30, 2022, as reported in the Issuer’s Report on Form 6-K filed with the Securities and Exchange Commission on August 29, 2022.

 

 

CUSIP No. 02290A102

Page 3 of 17

 

1.		Name of reporting persons   VHCP Co-Investment Holdings III, LLC
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
3.		SEC USE ONLY
4.		Citizenship or Place of Organization   Delaware

Number of Shares Beneficially Owned by Each Reporting Person With:	5.		Sole Voting Power   0
	6.		Shared Voting Power   26,740,0002
	7.		Sole Dispositive Power   0
	8.		Shared Dispositive Power   26,740,0002

9.		Aggregate Amount Beneficially Owned by Each Reporting Person   26,740,0002
10.		Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
11.		Percent of Class Represented by Amount in Row (9)   9.9%3
12.		Type of Reporting Person (See Instructions)   OO

 

1	Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G.

 

2

Consists of (i) 7,029,946 ordinary shares in the form of 1,004,278 American Depositary Shares (“ADSs”) held by Venrock Healthcare Capital Partners III, L.P., (ii) 703,262 ordinary shares in the form of 100,466 ADSs held by VHCP Co-Investment Holdings III, LLC and (iii) 19,006,792 ordinary shares in the form of 2,715,256 ADSs held by Venrock Healthcare Capital Partners EG, L.P. Each ADS represents seven (7) ordinary shares.

 

3	This percentage is calculated based upon 270,328,483 ordinary shares (including in the form of ADSs) outstanding as of June 30, 2022, as reported in the Issuer’s Report on Form 6-K filed with the Securities and Exchange Commission on August 29, 2022.

 

 

CUSIP No. 02290A102

Page 4 of 17

 

1.		Name of reporting persons   Venrock Healthcare Capital Partners EG, L.P.
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
3.		SEC USE ONLY
4.		Citizenship or Place of Organization   Delaware

Number of Shares Beneficially Owned by Each Reporting Person With:	5.		Sole Voting Power   0
	6.		Shared Voting Power   26,740,0002
	7.		Sole Dispositive Power   0
	8.		Shared Dispositive Power   26,740,0002

9.		Aggregate Amount Beneficially Owned by Each Reporting Person   26,740,0002
10.		Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
11.		Percent of Class Represented by Amount in Row (9)   9.9%3
12.		Type of Reporting Person (See Instructions)   PN

 

1	Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G.

 

2

Consists of (i) 7,029,946 ordinary shares in the form of 1,004,278 American Depositary Shares (“ADSs”) held by Venrock Healthcare Capital Partners III, L.P., (ii) 703,262 ordinary shares in the form of 100,466 ADSs held by VHCP Co-Investment Holdings III, LLC and (iii) 19,006,792 ordinary shares in the form of 2,715,256 ADSs held by Venrock Healthcare Capital Partners EG, L.P. Each ADS represents seven (7) ordinary shares.

 

3	This percentage is calculated based upon 270,328,483 ordinary shares (including in the form of ADSs) outstanding as of June 30, 2022, as reported in the Issuer’s Report on Form 6-K filed with the Securities and Exchange Commission on August 29, 2022.

  

 

CUSIP No. 02290A102

Page 5 of 17

 

1.		Name of reporting persons   VHCP Management III, LLC
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
3.		SEC USE ONLY
4.		Citizenship or Place of Organization   Delaware

Number of Shares Beneficially Owned by Each Reporting Person With:	5.		Sole Voting Power   0
	6.		Shared Voting Power   26,740,0002
	7.		Sole Dispositive Power   0
	8.		Shared Dispositive Power   26,740,0002

9.		Aggregate Amount Beneficially Owned by Each Reporting Person   26,740,0002
10.		Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
11.		Percent of Class Represented by Amount in Row (9)   9.9%3
12.		Type of Reporting Person (See Instructions)   OO

 

1	Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G.

 

2

Consists of (i) 7,029,946 ordinary shares in the form of 1,004,278 American Depositary Shares (“ADSs”) held by Venrock Healthcare Capital Partners III, L.P., (ii) 703,262 ordinary shares in the form of 100,466 ADSs held by VHCP Co-Investment Holdings III, LLC and (iii) 19,006,792 ordinary shares in the form of 2,715,256 ADSs held by Venrock Healthcare Capital Partners EG, L.P. Each ADS represents seven (7) ordinary shares.

 

3	This percentage is calculated based upon 270,328,483 ordinary shares (including in the form of ADSs) outstanding as of June 30, 2022, as reported in the Issuer’s Report on Form 6-K filed with the Securities and Exchange Commission on August 29, 2022.

 

 

CUSIP No. 02290A102

Page 6 of 17

 

1.		Name of reporting persons   VHCP Management EG, LLC
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
3.		SEC USE ONLY
4.		Citizenship or Place of Organization   Delaware

Number of Shares Beneficially Owned by Each Reporting Person With:	5.		Sole Voting Power   0
	6.		Shared Voting Power   26,740,0002
	7.		Sole Dispositive Power   0
	8.		Shared Dispositive Power   26,740,0002

9.		Aggregate Amount Beneficially Owned by Each Reporting Person   26,740,0002
10.		Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
11.		Percent of Class Represented by Amount in Row (9)   9.9%3
12.		Type of Reporting Person (See Instructions)   OO

 

1	Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G.

 

2

Consists of (i) 7,029,946 ordinary shares in the form of 1,004,278 American Depositary Shares (“ADSs”) held by Venrock Healthcare Capital Partners III, L.P., (ii) 703,262 ordinary shares in the form of 100,466 ADSs held by VHCP Co-Investment Holdings III, LLC and (iii) 19,006,792 ordinary shares in the form of 2,715,256 ADSs held by Venrock Healthcare Capital Partners EG, L.P. Each ADS represents seven (7) ordinary shares.

 

3	This percentage is calculated based upon 270,328,483 ordinary shares (including in the form of ADSs) outstanding as of June 30, 2022, as reported in the Issuer’s Report on Form 6-K filed with the Securities and Exchange Commission on August 29, 2022.

 

 

CUSIP No. 02290A102

Page 7 of 17

 

1.		Name of Reporting Persons   Shah, Nimish
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
3.		SEC USE ONLY
4.		Citizenship or Place of Organization   United States

Number of Shares Beneficially Owned by Each Reporting Person With:	5.		Sole Voting Power   0
	6.		Shared Voting Power   26,740,0002
	7.		Sole Dispositive Power   0
	8.		Shared Dispositive Power   26,740,0002

9.		Aggregate Amount Beneficially Owned by Each Reporting Person   26,740,0002
10.		Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
11.		Percent of Class Represented by Amount in Row (9)   9.9%3
12.		Type of Reporting Person (See Instructions)   IN

 

1	Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G.

 

2

Consists of (i) 7,029,946 ordinary shares in the form of 1,004,278 American Depositary Shares (“ADSs”) held by Venrock Healthcare Capital Partners III, L.P., (ii) 703,262 ordinary shares in the form of 100,466 ADSs held by VHCP Co-Investment Holdings III, LLC and (iii) 19,006,792 ordinary shares in the form of 2,715,256 ADSs held by Venrock Healthcare Capital Partners EG, L.P. Each ADS represents seven (7) ordinary shares.

 

3	This percentage is calculated based upon 270,328,483 ordinary shares (including in the form of ADSs) outstanding as of June 30, 2022, as reported in the Issuer’s Report on Form 6-K filed with the Securities and Exchange Commission on August 29, 2022.

 

 

CUSIP No. 02290A102

Page 8 of 17

 

1.		Name of Reporting Persons   Koh, Bong
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
3.		SEC USE ONLY
4.		Citizenship or Place of Organization   United States

Number of Shares Beneficially Owned by Each Reporting Person With:	5.		Sole Voting Power   0
	6.		Shared Voting Power   26,740,0002
	7.		Sole Dispositive Power   0
	8.		Shared Dispositive Power   26,740,0002

9.		Aggregate Amount Beneficially Owned by Each Reporting Person   26,740,0002
10.		Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
11.		Percent of Class Represented by Amount in Row (9)   9.9%3
12.		Type of Reporting Person (See Instructions)   IN

 

1	Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G.

 

2

Consists of (i) 7,029,946 ordinary shares in the form of 1,004,278 American Depositary Shares (“ADSs”) held by Venrock Healthcare Capital Partners III, L.P., (ii) 703,262 ordinary shares in the form of 100,466 ADSs held by VHCP Co-Investment Holdings III, LLC and (iii) 19,006,792 ordinary shares in the form of 2,715,256 ADSs held by Venrock Healthcare Capital Partners EG, L.P. Each ADS represents seven (7) ordinary shares.

 

3	This percentage is calculated based upon 270,328,483 ordinary shares (including in the form of ADSs) outstanding as of June 30, 2022, as reported in the Issuer’s Report on Form 6-K filed with the Securities and Exchange Commission on August 29, 2022.

 

 

CUSIP No. 02290A102

Page 9 of 17

 

Introductory Note: This Schedule 13G is filed on behalf of Venrock Healthcare Capital Partners III, L.P., a limited partnership organized under the laws of the State of Delaware (“VHCP III LP”), VHCP Co-Investment Holdings III, LLC, a limited liability company organized under the laws of the State of Delaware (“VHCP Co-Investment III”), Venrock Healthcare Capital Partners EG, L.P., a limited partnership organized under the laws of the State of Delaware (“VHCP EG”), VHCP Management III, LLC, a limited liability company organized under the laws of the State of Delaware (“VHCP Management III”), VHCP Management EG, LLC, a limited liability company organized under the laws of the State of Delaware (“VHCP Management EG” and collectively with VHCP III LP, VHCP Co-Investment III, VHCP EG and VHCP Management III, the “Venrock Entities”), Nimish Shah (“Shah”) and Bong Koh (“Koh”) in respect of the ordinary shares of Ambrx Biopharma Inc.

 

Item 1.

 

(a)

Name of Issuer

 

Ambrx Biopharma Inc.

 

(b)

Address of Issuer’s Principal Executive Offices

 

10975 Torrey Pines Road

La Jolla, California 92037

 

Item 2.

 

(a)

Name of Person Filing

 

Venrock Healthcare Capital Partners III, L.P.

VHCP Co-Investment Holdings III, LLC

Venrock Healthcare Capital Partners EG, L.P.

VHCP Management III, LLC

VHCP Management EG, LLC

Nimish Shah

Bong Koh

 

(b)

Address of Principal Business Office or, if none, Residence

 

	New York Office:	Palo Alto Office:
	7 Bryant Park	3340 Hillview Avenue
	23rd Floor	Palo Alto, CA 94304
	New York, NY 10018

 

(c)

Citizenship

 

All of the Venrock Entities were organized in Delaware. The individuals are both United States citizens.

 

(d)

Title of Class of Securities

 

Ordinary shares, par value $0.0001 per share.

 

(e)

CUSIP Number

 

02290A102. There is no CUSIP number assigned to the ordinary shares. The CUSIP number 02290A102 has been assigned to the American Depositary Shares (“ADSs”) of the Issuer, which are quoted on the New York Stock Exchange under the symbol “AMAM.” Each ADS represents seven (7) ordinary shares.

 

 

CUSIP No. 02290A102

Page 10 of 17

 

Item 3.

If this statement is filed pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:

 

Not applicable

 

Item 4.

Ownership

 

(a)

Amount Beneficially Owned as of February 27, 2023:

 

Venrock Healthcare Capital Partners III, L.P.			26,740,000	(1)
VHCP Co-Investment Holdings III, LLC			26,740,000	(1)
Venrock Healthcare Capital Partners EG, L.P.			26,740,000	(1)
VHCP Management III, LLC			26,740,000	(1)
VHCP Management EG, LLC			26,740,000	(1)
Nimish Shah			26,740,000	(1)
Bong Koh			26,740,000	(1)

 

(b)

Percent of Class as of February 27, 2023:

 

Venrock Healthcare Capital Partners III, L.P.			9.9	%
VHCP Co-Investment Holdings III, LLC			9.9	%
Venrock Healthcare Capital Partners EG, L.P.			9.9	%
VHCP Management III, LLC			9.9	%
VHCP Management EG, LLC			9.9	%
Nimish Shah			9.9	%
Bong Koh			9.9	%

 

(c)

Number of shares as to which the person has, as of February 27, 2023:

 

(i)

Sole power to vote or to direct the vote

 

Venrock Healthcare Capital Partners III, L.P.			0
VHCP Co-Investment Holdings III, LLC			0
Venrock Healthcare Capital Partners EG, L.P.			0
VHCP Management III, LLC			0
VHCP Management EG, LLC			0
Nimish Shah			0
Bong Koh			0

 

(ii)

Shared power to vote or to direct the vote

 

Venrock Healthcare Capital Partners III, L.P.			26,740,000	(1)
VHCP Co-Investment Holdings III, LLC			26,740,000	(1)
Venrock Healthcare Capital Partners EG, L.P.			26,740,000	(1)
VHCP Management III, LLC			26,740,000	(1)
VHCP Management EG, LLC			26,740,000	(1)
Nimish Shah			26,740,000	(1)
Bong Koh			26,740,000	(1)

 

 

CUSIP No. 02290A102

Page 11 of 17

 

(iii)

Sole power to dispose or to direct the disposition of

 

Venrock Healthcare Capital Partners III, L.P.			0
VHCP Co-Investment Holdings III, LLC			0
Venrock Healthcare Capital Partners EG, L.P.			0
VHCP Management III, LLC			0
VHCP Management EG, LLC			0
Nimish Shah			0
Bong Koh			0

 

(iv)

Shared power to dispose or to direct the disposition of

 

Venrock Healthcare Capital Partners III, L.P.			26,740,000	(1)
VHCP Co-Investment Holdings III, LLC			26,740,000	(1)
Venrock Healthcare Capital Partners EG, L.P.			26,740,000	(1)
VHCP Management III, LLC			26,740,000	(1)
VHCP Management EG, LLC			26,740,000	(1)
Nimish Shah			26,740,000	(1)
Bong Koh			26,740,000	(1)

 

(1)

Consists of (i) 7,029,946 ordinary shares in the form of 1,004,278 ADSs held by Venrock Healthcare Capital Partners III, L.P., (ii) 703,262 ordinary shares in the form of 100,466 ADSs held by VHCP Co-Investment Holdings III, LLC and (iii) 19,006,792 ordinary shares in the form of 2,715,256 ADSs held by Venrock Healthcare Capital Partners EG, L.P. VHCP Management III, LLC is the general partner of Venrock Healthcare Capital Partners III, L.P. and the manager of VHCP Co-Investment Holdings III, LLC. VHCP Management EG, LLC is the general partner of Venrock Healthcare Capital Partners EG, L.P. Messrs. Shah and Koh are the voting members of VHCP Management III, LLC and VHCP Management EG, LLC.

 

Item 5.

Ownership of Five Percent or Less of a Class

 

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following ¨.

  

Item 6.

Ownership of More than Five Percent on Behalf of Another Person

 

Not Applicable

  

Item 7.

Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.

 

Not Applicable

 

Item 8.

Identification and Classification of Members of the Group

 

Not Applicable

 

Item 9.

Notice of Dissolution of a Group

 

Not Applicable

 

Item 10.

Certification

 

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

 

 

CUSIP No. 02290A102

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SIGNATURE

 

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

 

Dated: February 27, 2023

 

Venrock Healthcare Capital Partners III, L.P.
By:	VHCP Management III, LLC
Its:	General Partner
By:	/s/ Sherman Souther
	Name: Sherman Souther
	Its: Authorized Signatory
VHCP Co-Investment Holdings III, LLC
By:	VHCP Management III, LLC
Its:	Manager
By:	/s/ Sherman Souther
	Name: Sherman Souther
	Its: Authorized Signatory
VHCP Management III, LLC
By:	/s/ Sherman Souther
	Name: Sherman Souther
	Its: Authorized Signatory
Venrock Healthcare Capital Partners EG, L.P.
By:	VHCP Management EG, LLC
Its:	General Partner
By:	/s/ Sherman Souther
	Name: Sherman Souther
	Its: Authorized Signatory
VHCP Management EG, LLC
By:	/s/ Sherman Souther
	Name: Sherman Souther
	Its: Authorized Signatory
Nimish Shah
/s/ Sherman Souther
Sherman Souther, Attorney-in-fact
Bong Koh
/s/ Sherman Souther
Sherman Souther, Attorney-in-fact

 

 

CUSIP No. 02290A102

Page 13 of 17

 

EXHIBITS

 

A:

Joint Filing Agreement

 

B:

Power of Attorney for Nimish Shah

 

C:

Power of Attorney for Bong Koh

 

 

CUSIP No. 02290A102

Page 14 of 17

 

EXHIBIT A

 

JOINT FILING AGREEMENT

 

In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the undersigned agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Ordinary Shares of Ambrx Biopharma Inc. and further agree that this agreement be included as an exhibit to such filing. Each party to the agreement expressly authorizes each other party to file on its behalf any and all amendments to such statement. Each party to this agreement agrees that this joint filing agreement may be signed in counterparts.

 

In evidence whereof, the undersigned have caused this Agreement to be executed on their behalf this 27^th day of February, 2023.

 

Venrock Healthcare Capital Partners III, L.P.
By:	VHCP Management III, LLC
Its:	General Partner
By:	/s/ Sherman Souther
	Name: Sherman Souther
	Its: Authorized Signatory
VHCP Co-Investment Holdings III, LLC
By:	VHCP Management III, LLC
Its:	Manager
By:	/s/ Sherman Souther
	Name: Sherman Souther
	Its: Authorized Signatory
VHCP Management III, LLC
By:	/s/ Sherman Souther
	Name: Sherman Souther
	Its: Authorized Signatory
Venrock Healthcare Capital Partners EG, L.P.
By:	VHCP Management EG, LLC
Its:	General Partner
By:	/s/ Sherman Souther
	Name: Sherman Souther
	Its: Authorized Signatory
VHCP Management EG, LLC
By:	/s/ Sherman Souther
	Name: Sherman Souther
	Its: Authorized Signatory

 

 

CUSIP No. 02290A102

Page 15 of 17

 

Nimish Shah
/s/ Sherman Souther
Sherman Souther, Attorney-in-fact
Bong Koh
/s/ Sherman Souther
Sherman Souther, Attorney-in-fact

 

 

CUSIP No. 02290A102

Page 16 of 17

 

EXHIBIT B

 

POWER OF ATTORNEY FOR NIMISH SHAH

 

KNOW ALL BY THESE PRESENTS, that the undersigned hereby constitutes and appoints each of David L. Stepp, Sherman G. Souther and Lisa D. Harris signing individually, the undersigned’s true and lawful attorney-in fact and agent to:

 

(i)

prepare execute and file, for and on behalf of the undersigned, any and all documents and filings that are required or advisable to be made with the United States Securities and Exchange Commission, any stock exchange or similar authority, under the Securities Exchange Act of 1934, as amended (the “Exchange Act”), and the rules and regulations promulgated thereunder, including without limitation (a) any Joint Filing Agreement under Rule 13d-1(k) of the Exchange Act (or any successor provision thereunder), Schedule 13D and Schedule 13G (or any successor schedules or forms adopted under the Exchange Act ) and any amendments thereto in accordance with Section 13 of the Exchange Act and the rules thereunder, and (b) Forms 3, 4 and 5 and any amendments thereto in accordance with Section 16(a) of the Exchange Act and the rules thereunder; and

 

(ii)

take any other action of any nature whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit, in the best interest of, or legally required by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve in such attorney-in-fact’s discretion.

 

The undersigned hereby grants to such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that such attorney-in-fact, or such attorney-in-fact’s substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted. The undersigned acknowledges that the foregoing attorney-in-fact, in serving in such capacity at the request of undersigned, is not assuming, nor is Venrock assuming, any of the undersigned’s responsibilities to comply with the Exchange Act, including without limitation Sections 13 and 16 of the Exchange Act.

 

This power of Attorney shall remain in full force and effect until the earliest to occur of (a) the undersigned is no longer required to file any form or document with respect to the undersigned’s holdings of and transactions in securities issued by a company, (b) revocation by the undersigned in a signed writing delivered to the foregoing attorney-in-fact, or (c) until such attorney-in-fact shall no longer be employed by VR Management, LLC (or its successor).

 

IN WITNESS WHEREOF, the undersigned has cause this Power of Attorney to be executed as of this 27^th day of February, 2023.

 

/s/ Nimish Shah

 

 

CUSIP No. 02290A102

Page 17 of 17

 

EXHIBIT C

 

POWER OF ATTORNEY FOR BONG KOH

 

KNOW ALL BY THESE PRESENTS, that the undersigned hereby constitutes and appoints each of David L. Stepp, Sherman G. Souther and Lisa D. Harris signing individually, the undersigned’s true and lawful attorney-in fact and agent to:

 

(i)

prepare execute and file, for and on behalf of the undersigned, any and all documents and filings that are required or advisable to be made with the United States Securities and Exchange Commission, any stock exchange or similar authority, under the Securities Exchange Act of 1934, as amended (the “Exchange Act”), and the rules and regulations promulgated thereunder, including without limitation (a) any Joint Filing Agreement under Rule 13d-1(k) of the Exchange Act (or any successor provision thereunder), Schedule 13D and Schedule 13G (or any successor schedules or forms adopted under the Exchange Act ) and any amendments thereto in accordance with Section 13 of the Exchange Act and the rules thereunder, and (b) Forms 3, 4 and 5 and any amendments thereto in accordance with Section 16(a) of the Exchange Act and the rules thereunder; and

 

(ii)

take any other action of any nature whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit, in the best interest of, or legally required by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve in such attorney-in-fact’s discretion.

 

The undersigned hereby grants to such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that such attorney-in-fact, or such attorney-in-fact’s substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted. The undersigned acknowledges that the foregoing attorney-in-fact, in serving in such capacity at the request of undersigned, is not assuming, nor is Venrock assuming, any of the undersigned’s responsibilities to comply with the Exchange Act, including without limitation Sections 13 and 16 of the Exchange Act.

 

This power of Attorney shall remain in full force and effect until the earliest to occur of (a) the undersigned is no longer required to file any form or document with respect to the undersigned’s holdings of and transactions in securities issued by a company, (b) revocation by the undersigned in a signed writing delivered to the foregoing attorney-in-fact, or (c) until such attorney-in-fact shall no longer be employed by VR Management, LLC (or its successor).

 

IN WITNESS WHEREOF, the undersigned has cause this Power of Attorney to be executed as of this 27^th day of February, 2023.

 

/s/ Bong Koh