Filing Details

The remainder of this cover page shall be filled out for a reporting persons initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

  NAME OF REPORTING PERSON

  I.R.S. IDENTIFICATION NO.

  Global Life Bioventure V S.à r.l. (Global Life)

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

  (a)  ☐        (b)  ☒ (1)

  SEC USE ONLY

  SOURCE OF FUNDS

  CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E)

  ☐

  CITIZENSHIP OR PLACE OF ORGANIZATION

  Luxembourg

NUMBER OF

SHARES

 BENEFICIALLY 

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER

1,788,160 shares, except that each of (i) Omega Fund V, L.P., the sole owner of Global Life (Omega Fund), (ii) Omega Fund V GP, L.P., the general partner of Omega Fund (Omega GP) and (iii) Omega Fund V G.P. Manager, Ltd., the general partner of Omega GP (Omega Ltd), may be deemed to have sole voting power with respect to the shares, and Vincent Ossipow (Ossipow), a class A manager of Global Life, and Otello Stampacchia (Stampacchia) Claudio Nessi (Nessi) and Anne-Mari Paster (Paster), the directors of Omega Ltd, may be deemed to have shared power to vote these shares.

  SHARED VOTING POWER

  See response to row 7.

  SOLE DISPOSITIVE POWER

1,788,160 shares, except that each of (i) Omega Fund, (ii) Omega GP and (iii) Omega Ltd may be deemed to have sole dispositive power with respect to the shares, and Ossipow, a class A manager of Global Life, and Stampacchia, Nessi and Paster, the directors of Omega Ltd, may be deemed to have shared dispositive power with respect to the shares.

  SHARED DISPOSITIVE POWER

  See response to row 9.

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

  1,788,160

  CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

  8.95%⁽²⁾

  TYPE OF REPORTING PERSON

  OO

This Schedule 13D is filed by Global Life, Omega Fund, Omega GP, Omega Ltd, Ossipow, Stampacchia, Nessi and Paster. Omega Ltd serves as the general partner of Omega GP, which serves as the general partner of Omega Fund, which holds all of the outstanding equity interests in Global Life; and each of Omega Fund, Omega GP and Omega Ltd may be deemed to own beneficially the shares held by Global Life. Stampacchia, Nessi and Paster are the directors of Omega Ltd, and Ossipow is the Class A Manager of Global Life, and such individuals may each be deemed to beneficially own the shares held by Global Life. The Reporting Persons may be deemed a group for purposes of Section 13 of the Exchange Act and expressly disclaim status as a group for purposes of this Schedule 13D. Each of Ossipow, Stampacchia, Nessi and Paster expressly disclaims beneficial ownership of the shares except to the extent of his or her pecuniary interest in the shares.

Based upon 19,968,340 shares of Common Stock outstanding as of August 4, 2020 as set forth in the Issuers Prospectus Supplement Form 424B5 filed with the Securities and Exchange Commission on August 5, 2020.

  NAME OF REPORTING PERSON

  I.R.S. IDENTIFICATION NO.

  Omega Fund V, L.P.

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

  (a)  ☐        (b)  ☒ (1)

  SEC USE ONLY

  SOURCE OF FUNDS

  CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E)

  ☐

  CITIZENSHIP OR PLACE OF ORGANIZATION

  Cayman Islands

NUMBER OF

SHARES

 BENEFICIALLY 

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER

1,788,160 shares, all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have sole voting power with respect to the shares, and Ossipow, a class A manager of Global Life, and Stampacchia, Nessi and Paster, the directors of Omega Ltd, may be deemed to have shared power to vote these shares.

  SHARED VOTING POWER

  See response to row 7.

  SOLE DISPOSITIVE POWER

1,788,160 shares, all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have dispositive voting power with respect to the shares, and Ossipow, a class A manager of Global Life, and Stampacchia, Nessi and Paster, the directors of Omega Ltd, may be deemed to have shared dispositive with respect to the shares.

  SHARED DISPOSITIVE POWER

  See response to row 9.

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

  1,788,160

  CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

  8.95%⁽²⁾

  TYPE OF REPORTING PERSON

  PN

This Schedule 13D is filed by Global Life, Omega Fund, Omega GP, Omega Ltd, Ossipow, Stampacchia, Nessi and Paster. Omega Ltd serves as the general partner of Omega GP, which serves as the general partner of Omega Fund, which holds all of the outstanding equity interests in Global Life; and each of Omega Fund, Omega GP and Omega Ltd may be deemed to own beneficially the shares held by Global Life. Stampacchia, Nessi and Paster are the directors of Omega Ltd, and Ossipow is the Class A Manager of Global Life, and such individuals may each be deemed to beneficially own the shares held by Global Life. The Reporting Persons may be deemed a group for purposes of Section 13 of the Exchange Act and expressly disclaim status as a group for purposes of this Schedule 13D. Each of Ossipow, Stampacchia, Nessi and Paster expressly disclaims beneficial ownership of the shares except to the extent of his or her pecuniary interest in the shares.

Based upon 19,968,340 shares of Common Stock outstanding as of August 4, 2020 as set forth in the Issuers Prospectus Supplement Form 424B5 filed with the Securities and Exchange Commission on August 5, 2020.

  NAME OF REPORTING PERSON

  I.R.S. IDENTIFICATION NO.

  Omega Fund V GP, L.P.

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

  (a)  ☐        (b)  ☒ (1)

  SEC USE ONLY

  SOURCE OF FUNDS

  CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E)

  ☐

  CITIZENSHIP OR PLACE OF ORGANIZATION

  Cayman Islands

NUMBER OF

SHARES

 BENEFICIALLY 

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER

1,788,160 shares, all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have sole voting power with respect to the shares, and Ossipow, a class A manager of Global Life, and Stampacchia, Nessi and Paster, the directors of Omega Ltd, may be deemed to have shared power to vote these shares.

  SHARED VOTING POWER

  See response to row 7.

  SOLE DISPOSITIVE POWER

1,788,160 shares, all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have dispositive voting power with respect to the shares, and Ossipow, a class A manager of Global Life, and Stampacchia, Nessi and Paster, the directors of Omega Ltd, may be deemed to have shared dispositive with respect to the shares.

  SHARED DISPOSITIVE POWER

  See response to row 9.

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

  1,788,160

  CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

  8.95%⁽²⁾

  TYPE OF REPORTING PERSON

  PN

This Schedule 13D is filed by Global Life, Omega Fund, Omega GP, Omega Ltd, Ossipow, Stampacchia, Nessi and Paster. Omega Ltd serves as the general partner of Omega GP, which serves as the general partner of Omega Fund, which holds all of the outstanding equity interests in Global Life; and each of Omega Fund, Omega GP and Omega Ltd may be deemed to own beneficially the shares held by Global Life. Stampacchia, Nessi and Paster are the directors of Omega Ltd, and Ossipow is the Class A Manager of Global Life, and such individuals may each be deemed to beneficially own the shares held by Global Life. The Reporting Persons may be deemed a group for purposes of Section 13 of the Exchange Act and expressly disclaim status as a group for purposes of this Schedule 13D. Each of Ossipow, Stampacchia, Nessi and Paster expressly disclaims beneficial ownership of the shares except to the extent of his or her pecuniary interest in the shares.

Based upon 19,968,340 shares of Common Stock outstanding as of August 4, 2020 as set forth in the Issuers Prospectus Supplement Form 424B5 filed with the Securities and Exchange Commission on August 5, 2020.

  NAME OF REPORTING PERSON

  I.R.S. IDENTIFICATION NO.

  Omega Fund V G.P. Manager, Ltd.

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

  (a)  ☐        (b)  ☒ (1)

  SEC USE ONLY

  SOURCE OF FUNDS

  CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E)

  ☐

  CITIZENSHIP OR PLACE OF ORGANIZATION

  Cayman Islands

NUMBER OF

SHARES

 BENEFICIALLY 

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER

1,788,160 shares, all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have sole voting power with respect to the shares, and Ossipow, a class A manager of Global Life, and Stampacchia, Nessi and Paster, the directors of Omega Ltd, may be deemed to have shared power to vote these shares.

  SHARED VOTING POWER

  See response to row 7.

  SOLE DISPOSITIVE POWER

1,788,160 shares, all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have dispositive voting power with respect to the shares, and Ossipow, a class A manager of Global Life, and Stampacchia, Nessi and Paster, the directors of Omega Ltd, may be deemed to have shared dispositive with respect to the shares.

  SHARED DISPOSITIVE POWER

  See response to row 9.

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

  1,788,160

  CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

  8.95%⁽²⁾

  TYPE OF REPORTING PERSON

  OO

This Schedule 13D is filed by Global Life, Omega Fund, Omega GP, Omega Ltd, Ossipow, Stampacchia, Nessi and Paster. Omega Ltd serves as the general partner of Omega GP, which serves as the general partner of Omega Fund, which holds all of the outstanding equity interests in Global Life; and each of Omega Fund, Omega GP and Omega Ltd may be deemed to own beneficially the shares held by Global Life. Stampacchia, Nessi and Paster are the directors of Omega Ltd, and Ossipow is the Class A Manager of Global Life, and such individuals may each be deemed to beneficially own the shares held by Global Life. The Reporting Persons may be deemed a group for purposes of Section 13 of the Exchange Act and expressly disclaim status as a group for purposes of this Schedule 13D. Each of Ossipow, Stampacchia, Nessi and Paster expressly disclaims beneficial ownership of the shares except to the extent of his or her pecuniary interest in the shares.

Based upon 19,968,340 shares of Common Stock outstanding as of August 4, 2020 as set forth in the Issuers Prospectus Supplement Form 424B5 filed with the Securities and Exchange Commission on August 5, 2020.

  NAME OF REPORTING PERSON

  I.R.S. IDENTIFICATION NO.

  Vincent Ossipow

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

  (a)  ☐        (b)  ☒ (1)

  SEC USE ONLY

  SOURCE OF FUNDS

  CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E)

  ☐

  CITIZENSHIP OR PLACE OF ORGANIZATION

  United States of America

NUMBER OF

SHARES

 BENEFICIALLY 

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER

  17,753 shares

  SHARED VOTING POWER

1,788,160 all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have sole voting power with respect to the shares, and Ossipow, the Class A Manager of Global Life, may be deemed to have shared power to vote these shares.

  SOLE DISPOSITIVE POWER

17,753 shares

  SHARED DISPOSITIVE POWER

1,788,160 all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have sole dispositive power with respect to the shares, and Ossipow, the Class A Manager of Global Life, may be deemed to have shared dispositive power with respect to the shares.

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

  1,805,913

  CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

  9.03%⁽²⁾

  TYPE OF REPORTING PERSON

  IN

This Schedule 13D is filed by Global Life, Omega Fund, Omega GP, Omega Ltd, Ossipow, Stampacchia, Nessi and Paster. Omega Ltd serves as the general partner of Omega GP, which serves as the general partner of Omega Fund, which holds all of the outstanding equity interests in Global Life; and each of Omega Fund, Omega GP and Omega Ltd may be deemed to own beneficially the shares held by Global Life. Stampacchia, Nessi and Paster are the directors of Omega Ltd, and Ossipow is the Class A Manager of Global Life, and such individuals may each be deemed to beneficially own the shares held by Global Life. The Reporting Persons may be deemed a group for purposes of Section 13 of the Exchange Act and expressly disclaim status as a group for purposes of this Schedule 13D. Each of Ossipow, Stampacchia, Nessi and Paster expressly disclaims beneficial ownership of the shares except to the extent of his or her pecuniary interest in the shares.

Based upon (i) 19,968,340 shares of Common Stock outstanding as of August 4, 2020 as set forth in the Issuers Prospectus Supplement Form 424B5 filed with the Securities and Exchange Commission on August 5, 2020 and (ii) 17,753 shares of Common Stock subject to the exercise of options held by Ossipow that have vested as, or will vest within 60 days, of August 5, 2020.

  NAME OF REPORTING PERSON

  I.R.S. IDENTIFICATION NO.

  Otello Stampacchia

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

  (a)  ☐        (b)  ☒ (1)

  SEC USE ONLY

  SOURCE OF FUNDS

  CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E)

  ☐

  CITIZENSHIP OR PLACE OF ORGANIZATION

  Italy

NUMBER OF

SHARES

 BENEFICIALLY 

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER

  0 shares

  SHARED VOTING POWER

1,788,160 all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have sole voting power with respect to the shares, and Stampacchia, a director of Omega Ltd, may be deemed to have shared power to vote these shares.

  SOLE DISPOSITIVE POWER

  0 shares

  SHARED DISPOSITIVE POWER

1,788,160 all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have sole dispositive power with respect to the shares, and Stampacchia, a director of Omega Ltd, may be deemed to have shared dispositive power with respect to the shares.

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

  1,788,160

  CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

  8.95%⁽²⁾

  TYPE OF REPORTING PERSON

  IN

This Schedule 13D is filed by Global Life, Omega Fund, Omega GP, Omega Ltd, Ossipow, Stampacchia, Nessi and Paster. Omega Ltd serves as the general partner of Omega GP, which serves as the general partner of Omega Fund, which holds all of the outstanding equity interests in Global Life; and each of Omega Fund, Omega GP and Omega Ltd may be deemed to own beneficially the shares held by Global Life. Stampacchia, Nessi and Paster are the directors of Omega Ltd, and Ossipow is the Class A Manager of Global Life, and such individuals may each be deemed to beneficially own the shares held by Global Life. The Reporting Persons may be deemed a group for purposes of Section 13 of the Exchange Act and expressly disclaim status as a group for purposes of this Schedule 13D. Each of Ossipow, Stampacchia, Nessi and Paster expressly disclaims beneficial ownership of the shares except to the extent of his or her pecuniary interest in the shares.

Based upon 19,968,340 shares of Common Stock outstanding as of August 4, 2020 as set forth in the Issuers Prospectus Supplement Form 424B5 filed with the Securities and Exchange Commission on August 5, 2020.

  NAME OF REPORTING PERSON

  I.R.S. IDENTIFICATION NO.

  Claudio Nessi

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

  (a)  ☐        (b)  ☒ (1)

  SEC USE ONLY

  SOURCE OF FUNDS

  CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E)

  ☐

  CITIZENSHIP OR PLACE OF ORGANIZATION

  Switzerland

NUMBER OF

SHARES

 BENEFICIALLY 

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER

  0 shares

  SHARED VOTING POWER

1,788,160 all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have sole voting power with respect to the shares, and Nessi, a director of Omega Ltd, may be deemed to have shared power to vote these shares.

  SOLE DISPOSITIVE POWER

  0 shares

  SHARED DISPOSITIVE POWER

1,788,160 all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have sole dispositive power with respect to the shares, and Nessi, a director of Omega Ltd, may be deemed to have shared dispositive power with respect to the shares.

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

  1,788,160

  CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

  8.95%⁽²⁾

  TYPE OF REPORTING PERSON

  IN

This Schedule 13D is filed by Global Life, Omega Fund, Omega GP, Omega Ltd, Ossipow, Stampacchia, Nessi and Paster. Omega Ltd serves as the general partner of Omega GP, which serves as the general partner of Omega Fund, which holds all of the outstanding equity interests in Global Life; and each of Omega Fund, Omega GP and Omega Ltd may be deemed to own beneficially the shares held by Global Life. Stampacchia, Nessi and Paster are the directors of Omega Ltd, and Ossipow is the Class A Manager of Global Life, and such individuals may each be deemed to beneficially own the shares held by Global Life. The Reporting Persons may be deemed a group for purposes of Section 13 of the Exchange Act and expressly disclaim status as a group for purposes of this Schedule 13D. Each of Ossipow, Stampacchia, Nessi and Paster expressly disclaims beneficial ownership of the shares except to the extent of his or her pecuniary interest in the shares.

Based upon 19,968,340 shares of Common Stock outstanding as of August 4, 2020 as set forth in the Issuers Prospectus Supplement Form 424B5 filed with the Securities and Exchange Commission on August 5, 2020.

  NAME OF REPORTING PERSON

  I.R.S. IDENTIFICATION NO.

  Anne-Mari Paster

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

  (a)  ☐        (b)  ☒ (1)

  SEC USE ONLY

  SOURCE OF FUNDS

  CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E)

  ☐

  CITIZENSHIP OR PLACE OF ORGANIZATION

  United States of America

NUMBER OF

SHARES

 BENEFICIALLY 

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER

  0 shares

  SHARED VOTING POWER

1,788,160 all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP, may be deemed to have sole voting power with respect to the shares, and Paster, a director of Omega Ltd, may be deemed to have shared power to vote these shares.

  SOLE DISPOSITIVE POWER

  0 shares

  SHARED DISPOSITIVE POWER

1,788,160 all of which are directly owned by Global Life. Omega Fund, the sole owner of Global Life, Omega GP, the general partner of Omega Fund and Omega Ltd, the general partner of Omega GP , may be deemed to have sole dispositive power with respect to the shares, and Paster, a director of Omega Ltd, may be deemed to have shared dispositive power with respect to the shares.

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

  1,788,160

  CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

  8.95%⁽²⁾

  TYPE OF REPORTING PERSON

  IN

This Schedule 13D is filed by Global Life, Omega Fund, Omega GP, Omega Ltd, Ossipow, Stampacchia, Nessi and Paster. Omega Ltd serves as the general partner of Omega GP, which serves as the general partner of Omega Fund, which holds all of the outstanding equity interests in Global Life; and each of Omega Fund, Omega GP and Omega Ltd may be deemed to own beneficially the shares held by Global Life. Stampacchia, Nessi and Paster are the directors of Omega Ltd, and Ossipow is the Class A Manager of Global Life, and such individuals may each be deemed to beneficially own the shares held by Global Life. The Reporting Persons may be deemed a group for purposes of Section 13 of the Exchange Act and expressly disclaim status as a group for purposes of this Schedule 13D. Each of Ossipow, Stampacchia, Nessi and Paster expressly disclaims beneficial ownership of the shares except to the extent of his or her pecuniary interest in the shares.

Based upon 19,968,340 shares of Common Stock outstanding as of August 4, 2020 as set forth in the Issuers Prospectus Supplement Form 424B5 filed with the Securities and Exchange Commission on August 5, 2020.

Security and Issuer

Identity and Background

Source and Amount of Funds or Other Consideration

Global Life(1)(2)(3)

Omega Fund(1)(2)(3)

Omega GP(1)(2)(3)

Omega Ltd.(1)(2)(3)

Ossipow(2)(3)(4)

Nessi(1)(2)(3)

Stampacchia(1)(2)(3)

Paster(1)(2)(3)

The percentage is based upon 19,968,340 shares of Common Stock outstanding as of August 4, 2020 as set forth in the Issuers Prospectus Supplement Form 424B5 filed with the Securities and Exchange Commission on August 5, 2020.

Global Life owns 1,788,160 shares of the Common Stock. Omega Ltd serves as the general partner of Omega GP, which serves as the general partner of Omega Fund, which holds all of the outstanding equity interests in Global Life; and each of Omega Fund, Omega GP and Omega Ltd may be deemed to own beneficially the shares held by Global Life. Stampacchia, Nessi and Paster are the directors of Omega Ltd, and Ossipow is the Class A Manager of Global Life, and such individuals may each be deemed to beneficially own the shares held by Global Life.

The Reporting Persons may be deemed a group for purposes of Section 13 of the Exchange Act and expressly disclaim status as a group for purposes of this Schedule 13D. Each of Ossipow, Stampacchia, Nessi and Paster expressly disclaims beneficial ownership of the shares except to the extent of his or her pecuniary interest in the shares.

The percentage is based upon (i) 19,968,340 shares of Common Stock outstanding as of August 4, 2020 as set forth in the Issuers Prospectus Supplement Form 424B5 filed with the Securities and Exchange Commission on August 5, 2020 and (ii) 17,753 shares of Common Stock subject to the exercise of options held by Ossipow that have vested as, or will vest within 60 days, of August 5, 2020.

Material to be Filed as Exhibits

Agreement of Joint Filing, dated April 22, 2019, by and among the Reporting Persons (incorporated herein by reference to Exhibit A to Schedule 13D filed on April 22, 2019).