Filing Details

The remainder of this cover page shall be filled out for a reporting persons initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

  NAMES OF REPORTING PERSONS

  Ernest Loumaye

  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

  (a)  ☐        (b)  ☒

  SEC USE ONLY

  CITIZENSHIP OR PLACE OF ORGANIZATION

  Belgium

NUMBER OF

SHARES

 BENEFICIALLY 

OWNED BY

EACH

REPORTING

PERSON

WITH

  SOLE VOTING POWER

  4,740,756

  SHARED VOTING POWER

  0

  SOLE DISPOSITIVE POWER

  4,740,756

  SHARED DISPOSITIVE POWER

  0

  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

  4,740,756

  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)

  ☐

  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

  6.1% (1)

  TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

  IN

This percentage is calculated based on 77,971,461 of the Issuers Common Shares (excluding 7,249,010 treasury shares) reported by the Issuer to be outstanding as of September 30, 2021 in Exhibit 99.1 attached to the Issuers Report on Form 6-K, as filed with the Securities and Exchange Commission on November 4, 2021 and assumes the exercise of 825,306 options held by Dr. Loumaye that are exercisable within 60 days of December 31, 2021.

Name of Issuer:

Address of Issuers principal executive offices:

2(a) Name of Reporting Persons filing:

Address or principal business office or, if none, residence:

Citizenship:

Title of class of securities:

CUSIP No.:

If this statement is filed pursuant to §§ 240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filings is a:

Ownership

Ernest Loumaye⁽¹⁾⁽²⁾

This percentage is calculated based on 77,971,461 of the Issuers Common Shares (excluding 7,249,010 treasury shares) reported by the Issuer to be outstanding as of September 30, 2021 in Exhibit 99.1 attached to the Issuers Report on Form 6-K, as filed with the Securities and Exchange Commission on November 4, 2021, and assumes the exercise of 825,306 options held by Dr. Loumaye that are exercisable within 60 days of December 31, 2021.

As of December 31, 2021, Dr. Loumaye beneficially owned 4,740,756 shares of the Issuers Common Shares consisting of (i) 3,915,450 Common Shares owned directly by him and (ii) options to purchase 825,306 Common Shares exercisable within 60 days of December 31, 2021.

Ownership of Five Percent or Less of a Class

Ownership of More than Five Percent on Behalf of Another Person

Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person

Identification and Classification of Members of the Group

Notice of Dissolution of Group

Certifications

/s/ Ernest Loumaye