Filing Details

The remainder of this cover page shall be filled out for a reporting persons initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

  Names of Reporting Persons

  Frazier Healthcare VI, L.P.

  Check the Appropriate Box if a Member of a Group (see instructions)

  (a)  ☐        (b)  ☒

  SEC USE ONLY

  Citizenship or Place of Organization

  Delaware

Number of

Shares

 Beneficially 

Owned by

Each

Reporting

Person

With:

  Sole Voting Power

  0 shares

  Shared Voting Power

  1,651,357 shares (1)

  Sole Dispositive Power

  0 shares

  Shared Dispositive Power

  1,651,357 shares (1)

  Aggregate Amount Beneficially Owned by Each Reporting Person

  1,651,357 shares (1)

  Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

  ☐

  Percent of Class Represented by Amount in Row 9

  2.0% (2)

  Type of Reporting Person (see instructions)

  PN

Consists of 1,651,357shares of Common Stock held directly by Frazier Healthcare VI, L.P. FHM VI, L.P. is the general partner of Frazier Healthcare VI, L.P. and FHM VI, L.L.C. is the general partner of FHM VI, L.P. James N. Topper, Patrick J. Heron, Alan Frazier, Nader Naini and Nathan Every are the members of FHM VI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Healthcare VI, L.P.

Based on 82,571,078 shares of Common Stock outstanding on November 5, 2021 as set forth in the Issuers Form 10-Q filed with the SEC on November 12, 2021.

  Names of Reporting Persons

  FHM VI, L.P.

  Check the Appropriate Box if a Member of a Group (see instructions)

  (a)  ☐        (b)  ☒

  SEC USE ONLY

  Citizenship or Place of Organization

  Delaware

Number of

Shares

 Beneficially 

Owned by

Each

Reporting

Person

With:

  Sole Voting Power

  0 shares

  Shared Voting Power

  1,651,357 shares (1)

  Sole Dispositive Power

  0 shares

  Shared Dispositive Power

  1,651,357 shares (1)

  Aggregate Amount Beneficially Owned by Each Reporting Person

  1,651,357 shares (1)

  Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

  ☐

  Percent of Class Represented by Amount in Row 9

  2.0% (2)

  Type of Reporting Person (see instructions)

  PN

Consists of 1,651,357shares of Common Stock held directly by Frazier Healthcare VI, L.P. FHM VI, L.P. is the general partner of Frazier Healthcare VI, L.P. and FHM VI, L.L.C. is the general partner of FHM VI, L.P. James N. Topper, Patrick J. Heron, Alan Frazier, Nader Naini and Nathan Every are the members of FHM VI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Healthcare VI, L.P.

Based on 82,571,078 shares of Common Stock outstanding on November 5, 2021 as set forth in the Issuers Form 10-Q filed with the SEC on November 12, 2021.

  Names of Reporting Persons

  FHM VI, L.L.C.

  Check the Appropriate Box if a Member of a Group (see instructions)

  (a)  ☐        (b)  ☒

  SEC USE ONLY

  Citizenship or Place of Organization

  Delaware

Number of

Shares

 Beneficially 

Owned by

Each

Reporting

Person

With:

  Sole Voting Power

  0 shares

  Shared Voting Power

  1,651,357 shares (1)

  Sole Dispositive Power

  0 shares

  Shared Dispositive Power

  1,651,357 shares (1)

  Aggregate Amount Beneficially Owned by Each Reporting Person

  1,651,357 shares (1)

  Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

  ☐

  Percent of Class Represented by Amount in Row 9

  2.0% (2)

  Type of Reporting Person (see instructions)

  OO

Consists of 1,651,357shares of Common Stock held directly by Frazier Healthcare VI, L.P. FHM VI, L.P. is the general partner of Frazier Healthcare VI, L.P. and FHM VI, L.L.C. is the general partner of FHM VI, L.P. James N. Topper, Patrick J. Heron, Alan Frazier, Nader Naini and Nathan Every are the members of FHM VI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Healthcare VI, L.P.

Based on 82,571,078 shares of Common Stock outstanding on November 5, 2021 as set forth in the Issuers Form 10-Q filed with the SEC on November 12, 2021.

  Names of Reporting Persons

  James N. Topper

  Check the Appropriate Box if a Member of a Group (see instructions)

  (a)  ☐        (b)  ☒

  SEC USE ONLY

  Citizenship or Place of Organization

  United States Citizen

Number of

Shares

 Beneficially 

Owned by

Each

Reporting

Person

With:

  Sole Voting Power

  0 shares

  Shared Voting Power

  1,651,357 shares (1)

  Sole Dispositive Power

  0 shares

  Shared Dispositive Power

  1,651,357 shares (1)

  Aggregate Amount Beneficially Owned by Each Reporting Person

  1,651,357 shares (1)

  Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

  ☐

  Percent of Class Represented by Amount in Row 9

  2.0% (2)

  Type of Reporting Person (see instructions)

  IN

Consists of 1,651,357shares of Common Stock held directly by Frazier Healthcare VI, L.P. FHM VI, L.P. is the general partner of Frazier Healthcare VI, L.P. and FHM VI, L.L.C. is the general partner of FHM VI, L.P. James N. Topper, Patrick J. Heron, Alan Frazier, Nader Naini and Nathan Every are the members of FHM VI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Healthcare VI, L.P.

Based on 82,571,078 shares of Common Stock outstanding on November 5, 2021 as set forth in the Issuers Form 10-Q filed with the SEC on November 12, 2021.

  Names of Reporting Persons

  Patrick J. Heron

  Check the Appropriate Box if a Member of a Group (see instructions)

  (a)  ☐        (b)  ☒

  SEC USE ONLY

  Citizenship or Place of Organization

  United States Citizen

Number of

Shares

 Beneficially 

Owned by

Each

Reporting

Person

With:

  Sole Voting Power

  0 shares

  Shared Voting Power

  1,651,357 shares (1)

  Sole Dispositive Power

  0 shares

  Shared Dispositive Power

  1,651,357 shares (1)

  Aggregate Amount Beneficially Owned by Each Reporting Person

  1,651,357 shares (1)

  Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

  ☐

  Percent of Class Represented by Amount in Row 9

  2.0% (2)

  Type of Reporting Person (see instructions)

  IN

Consists of 1,651,357shares of Common Stock held directly by Frazier Healthcare VI, L.P. FHM VI, L.P. is the general partner of Frazier Healthcare VI, L.P. and FHM VI, L.L.C. is the general partner of FHM VI, L.P. James N. Topper, Patrick J. Heron, Alan Frazier, Nader Naini and Nathan Every are the members of FHM VI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Healthcare VI, L.P.

Based on 82,571,078 shares of Common Stock outstanding on November 5, 2021 as set forth in the Issuers Form 10-Q filed with the SEC on November 12, 2021.

  Names of Reporting Persons

  Alan Frazier

  Check the Appropriate Box if a Member of a Group (see instructions)

  (a)  ☐        (b)  ☒

  SEC USE ONLY

  Citizenship or Place of Organization

  United States Citizen

Number of

Shares

 Beneficially 

Owned by

Each

Reporting

Person

With:

  Sole Voting Power

  0 shares

  Shared Voting Power

  1,651,357 shares (1)

  Sole Dispositive Power

  0 shares

  Shared Dispositive Power

  1,651,357 shares (1)

  Aggregate Amount Beneficially Owned by Each Reporting Person

  1,651,357 shares (1)

  Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

  ☐

  Percent of Class Represented by Amount in Row 9

  2.0% (2)

  Type of Reporting Person (see instructions)

  IN

Consists of 1,651,357shares of Common Stock held directly by Frazier Healthcare VI, L.P. FHM VI, L.P. is the general partner of Frazier Healthcare VI, L.P. and FHM VI, L.L.C. is the general partner of FHM VI, L.P. James N. Topper, Patrick J. Heron, Alan Frazier, Nader Naini and Nathan Every are the members of FHM VI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Healthcare VI, L.P.

Based on 82,571,078 shares of Common Stock outstanding on November 5, 2021 as set forth in the Issuers Form 10-Q filed with the SEC on November 12, 2021.

  Names of Reporting Persons

  Nader Naini

  Check the Appropriate Box if a Member of a Group (see instructions)

  (a)  ☐        (b)  ☒

  SEC USE ONLY

  Citizenship or Place of Organization

  United States Citizen

Number of

Shares

 Beneficially 

Owned by

Each

Reporting

Person

With:

  Sole Voting Power

  0 shares

  Shared Voting Power

  1,651,357 shares (1)

  Sole Dispositive Power

  0 shares

  Shared Dispositive Power

  1,651,357 shares (1)

  Aggregate Amount Beneficially Owned by Each Reporting Person

  1,651,357 shares (1)

  Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

  ☐

  Percent of Class Represented by Amount in Row 9

  2.0% (2)

  Type of Reporting Person (see instructions)

  IN

Consists of 1,651,357shares of Common Stock held directly by Frazier Healthcare VI, L.P. FHM VI, L.P. is the general partner of Frazier Healthcare VI, L.P. and FHM VI, L.L.C. is the general partner of FHM VI, L.P. James N. Topper, Patrick J. Heron, Alan Frazier, Nader Naini and Nathan Every are the members of FHM VI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Healthcare VI, L.P.

Based on 82,571,078 shares of Common Stock outstanding on November 5, 2021 as set forth in the Issuers Form 10-Q filed with the SEC on November 12, 2021.

  Names of Reporting Persons

  Nathan Every

  Check the Appropriate Box if a Member of a Group (see instructions)

  (a)  ☐        (b)  ☒

  SEC USE ONLY

  Citizenship or Place of Organization

  United States Citizen

Number of

Shares

 Beneficially 

Owned by

Each

Reporting

Person

With:

  Sole Voting Power

  0 shares

  Shared Voting Power

  1,651,357 shares (1)

  Sole Dispositive Power

  0 shares

  Shared Dispositive Power

  1,651,357 shares (1)

  Aggregate Amount Beneficially Owned by Each Reporting Person

  1,651,357 shares (1)

  Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

  ☐

  Percent of Class Represented by Amount in Row 9

  2.0% (2)

  Type of Reporting Person (see instructions)

  IN

Consists of 1,651,357shares of Common Stock held directly by Frazier Healthcare VI, L.P. FHM VI, L.P. is the general partner of Frazier Healthcare VI, L.P. and FHM VI, L.L.C. is the general partner of FHM VI, L.P. James N. Topper, Patrick J. Heron, Alan Frazier, Nader Naini and Nathan Every are the members of FHM VI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Healthcare VI, L.P.

Based on 82,571,078 shares of Common Stock outstanding on November 5, 2021 as set forth in the Issuers Form 10-Q filed with the SEC on November 12, 2021.

Name of Person Filing:

The entities and persons filing this statement (collectively, the Reporting Persons) are:

Frazier Healthcare VI, L.P. (FH VI)

FHM VI, L.P.

FHM VI, L.L.C.

James N. Topper (Topper)

Patrick J. Heron (Heron)

Alan Frazier (Frazier)

Nader Naini (Naini)

Nathan Every (Every and together with Topper, Heron, Frazier and Naini, the Members)

Address of Principal Business Office or, if none, Residence:

The address and principal business office of the Reporting Persons is:

c/o Frazier Healthcare Partners

601 Union Street, Suite 3200

Seattle, Washington 98101

☐   Broker or dealer registered under Section 15 of the Act (15 U.S.C. 78o);

☐   Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);

☐   Insurance company as defined in section 3(a)19) of the Act (15 U.S.C. 78c);

☐   Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);

☐   An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E);

☐   An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F);

☐   A parent holding company or control person in accordance with §240.13d-1(b)(1)(ii)(G);

☐   A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

☐   A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

☐   A non-U.S. institution in accordance with §240.13d1(b)(1)(ii)(J);

☐   Group, in accordance with §240.13d1(b)(1)(ii)(K).

Ownership

Amount Beneficially Owned: See Row 9 of cover page for each Reporting Person.

Percent of Class: See Row 11 of cover page for each Reporting Person

Number of shares as to which the person has:

Sole power to vote or to direct the vote: See Row 5 of cover page for each Reporting Person.

Shared power to vote or to direct the vote: See Row 6 of cover page for each Reporting Person.

Sole power to dispose or to direct the disposition of: See Row 7 of cover page for each Reporting Person.

Shared power to dispose or to direct the disposition of: See Row 8 of cover page for each Reporting Person.

Ownership of 5 Percent or Less of a Class

Ownership of More than 5 Percent on Behalf of Another Person

Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.

Identification and Classification of Members of the Group

Notice of Dissolution of a Group

Certification

/s/ Steve R. Bailey

/s/ Steve R. Bailey

/s/ Steve R. Bailey

*

*

*

*

*

/s/ Steve R. Bailey

This Schedule 13G was executed by Steve R. Bailey on behalf of the individuals listed above pursuant to a Power of Attorney, a copy of which was filed with the SEC on February 24, 2017.