Filing Details

The remainder of this cover page shall be filled out for a reporting persons initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

  Name of Reporting Person:

  Novo Holdings A/S

  Check the Appropriate Box if a Member of Group (See Instructions):

  (a)  ☐        (b)  ☐

  SEC Use Only:

  Citizenship or Place of Organization:

  Denmark

Number of

Shares

 Beneficially 

Owned By

Each

Reporting

Person

With:

  Sole Voting Power:

  3,549,320

  Shared Voting Power:

  0

  Sole Dispositive Power:

  3,549,320

  Shared Dispositive Power:

  0

  Aggregate Amount Beneficially Owned by Each Reporting Person:

  3,549,320

  Check if the Aggregate Amount in Row (9) Excludes Certain Shares:

  ☐

  Percent of Class Represented By Amount In Row (9):

  16.1% (1)

  Type of Reporting Person:

  CO

Based upon 22,117,647 shares of the Issuers Common Stock outstanding as of October 30, 2020, as reported in the Issuers Form 10-Q filed with the Securities and Exchange Commission (the SEC) on November 4, 2020.

(a)    Name of Issuer:

Address of Issuers Principal Executive Offices:

(a)    Name of Person Filing:

Address or Principal Business Office or, if none, Residence:

Citizenship or Place of Organization:

Title of Class of Securities:

CUSIP Number:

If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

Ownership:

(a)

(b)

(c)

Novo Holdings A/S, through its Board of Directors (the Novo Board), has the sole power to vote and dispose of the securities of the Issuer held by Novo Holdings A/S (the Novo Shares). The Novo Board may exercise voting and dispositive control over the Novo Shares only with the support of a majority of the Novo Board. As such, no individual member of the Novo Board is deemed to hold any beneficial ownership or reportable pecuniary interest in the Novo Shares. Scott Beardsley, who is employed as a Partner at Novo Ventures (US) Inc., which provides certain consultancy services to Novo Holdings A/S, ceased service as a member of the board of directors of the Issuer on February 12, 2021. Mr. Beardsley is not deemed a beneficial owner of, and does not have a reportable pecuniary interest in, the Novo Shares.

Based upon 22,117,647 shares of the Issuers Common Stock outstanding as of October 30, 2020, as reported in the Issuers Form 10-Q filed with the SEC on November 4, 2020.

Ownership of Five Percent or Less of a Class:

Ownership of More Than Five Percent on Behalf of Another Person:

Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person:

Identification and Classification of Members of the Group:

Notice of Dissolution of Group:

Certifications:

/s/ Peter Haahr